prikaz prve stranice dokumenta Altered leptin, adiponectin, resistin and ghrelin secretion may represent an intrinsic polycystic ovary syndrome abnormality
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Scientific paper - Original scientific paper
Altered leptin, adiponectin, resistin and ghrelin secretion may represent an intrinsic polycystic ovary syndrome abnormality
Gynecological Endocrinology, 35 (2019), 5; 401-405. https://doi.org/10.1080/09513590.2018.1534096
Pavičić Baldani, Dinka; Škrgatić, Lana; Kasum, Miro; Zlopaša, Gordan; Kralik Oguić, Saša; Herman, Mislav

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Pavičić Baldani, D., Škrgatić, L., Kasum, M., Zlopaša, G., Kralik Oguić, S. & Herman, M. (2019). Altered leptin, adiponectin, resistin and ghrelin secretion may represent an intrinsic polycystic ovary syndrome abnormality. Gynecological Endocrinology, 35. (5), 401-405. doi: 10.1080/09513590.2018.1534096

Pavičić Baldani, Dinka, et al. "Altered leptin, adiponectin, resistin and ghrelin secretion may represent an intrinsic polycystic ovary syndrome abnormality." Gynecological Endocrinology, vol. 35, no. 5, 2019, pp. 401-405. https://doi.org/10.1080/09513590.2018.1534096

Pavičić Baldani, Dinka, Lana Škrgatić, Miro Kasum, Gordan Zlopaša, Saša Kralik Oguić and Mislav Herman. "Altered leptin, adiponectin, resistin and ghrelin secretion may represent an intrinsic polycystic ovary syndrome abnormality." Gynecological Endocrinology 35, no. 5 (2019): 401-405. https://doi.org/10.1080/09513590.2018.1534096

Pavičić Baldani, D., et al. (2019) 'Altered leptin, adiponectin, resistin and ghrelin secretion may represent an intrinsic polycystic ovary syndrome abnormality', Gynecological Endocrinology, 35(5), pp. 401-405. doi: 10.1080/09513590.2018.1534096

Pavičić Baldani D, Škrgatić L, Kasum M, Zlopaša G, Kralik Oguić S, Herman M. Altered leptin, adiponectin, resistin and ghrelin secretion may represent an intrinsic polycystic ovary syndrome abnormality. Gynecological Endocrinology [Internet]. 2019 May [cited 2024 November 26];35(5):401-405. doi: 10.1080/09513590.2018.1534096

D. Pavičić Baldani, L. Škrgatić, M. Kasum, G. Zlopaša, S. Kralik Oguić and M. Herman, "Altered leptin, adiponectin, resistin and ghrelin secretion may represent an intrinsic polycystic ovary syndrome abnormality", Gynecological Endocrinology, vol. 35, no. 5, pp. 401-405, May 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:337556. [Accessed: 26 November 2024]

Metadata
Title (english)Altered leptin, adiponectin, resistin and ghrelin secretion may represent an intrinsic polycystic ovary syndrome abnormality
AuthorDinka Pavičić Baldani
AuthorLana Škrgatić
AuthorMiro Kasum
AuthorGordan Zlopaša
AuthorSaša Kralik Oguić
AuthorMislav Herman
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Gynecology and Obstetrics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract (english)
The aim of the study was to investigate whether altered adipose tissue secretion of various adipokines is secondary to obesity, hyperandrogenism, and hyperinsulinemia or intrinsic to polycystic ovary syndrome (PCOS). This cross-sectional study included 151 women diagnosed with PCOS by the Rotterdam criteria and 95 healthy women matched by age, body mass index (BMI), and waist-to-hip ratio (WHR). Clinical, biochemical, and hormonal characteristics were assessed. Serum concentrations of ghrelin and adiponectin were found to be significantly lower and concentrations of leptin and resistin significantly higher in women with PCOS than in healthy women matched by age, BMI, and WHR. A PCOS diagnosis made the largest contribution to predicting serum levels of leptin, adiponectin, resistin, and ghrelin in all stepwise multiple regression models, which included PCOS diagnosis, BMI, WHR, luteinizing hormone, total testosterone, free testosterone and homeostatic model assessment of insulin resistance as independent predictors. Leptin, adiponectin, ghrelin and resistin levels may serve as independent biomarkers for the diagnosis of PCOS.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleGynecological Endocrinology
Numberingvol. 35, no. 5, pp. 401-405
p-ISSN0951-3590
e-ISSN1473-0766
DOIhttps://doi.org/10.1080/09513590.2018.1534096
URN:NBNurn:nbn:hr:105:337556
Publication2019-05
Document URLhttps://www.tandfonline.com/doi/full/10.1080/09513590.2018.1534096
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-02-03 10:37:28