prikaz prve stranice dokumenta Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)
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Scientific paper - Original scientific paper
Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)
International Journal of Infectious Diseases, 89 (2019); 3-9. https://doi.org/10.1016/j.ijid.2019.09.008
Vrdoljak, Maja; Gužvinec, Marija; Trkulja, Vladimir; Butić, Iva; Ivić, Ivo; Krželj, Vjekoslav; Tonkić, Marija; Hegeduš Jungvirth, Marija; Payerl Pal, Marina; Tešović, Goran

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Vrdoljak, M., Gužvinec, M., Trkulja, V., Butić, I., Ivić, I., Krželj, V. ... Tešović, G. (2019). Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014). International Journal of Infectious Diseases, 89., 3-9. doi: 10.1016/j.ijid.2019.09.008

Vrdoljak, Maja, et al. "Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)." International Journal of Infectious Diseases, vol. 89, 2019, pp. 3-9. https://doi.org/10.1016/j.ijid.2019.09.008

Vrdoljak, Maja, Marija Gužvinec, Vladimir Trkulja, Iva Butić, Ivo Ivić, Vjekoslav Krželj, Marija Tonkić, Marija Hegeduš Jungvirth, Marina Payerl Pal and Goran Tešović. "Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)." International Journal of Infectious Diseases 89 (2019): 3-9. https://doi.org/10.1016/j.ijid.2019.09.008

Vrdoljak, M., et al. (2019) 'Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)', International Journal of Infectious Diseases, 89, pp. 3-9. doi: 10.1016/j.ijid.2019.09.008

Vrdoljak M, Gužvinec M, Trkulja V, Butić I, Ivić I, Krželj V, and sur.. Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014). International Journal of Infectious Diseases [Internet]. 2019 December [cited 2024 November 23];89:3-9. doi: 10.1016/j.ijid.2019.09.008

M. Vrdoljak, et al., "Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)", International Journal of Infectious Diseases, vol. 89, pp. 3-9, December 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:477113. [Accessed: 23 November 2024]

Metadata
Title (english)Distribution of rotavirus genotypes in three Croatian regions among children ≤5 years of age (2012–2014)
AuthorMaja Vrdoljak
AuthorMarija Gužvinec
AuthorVladimir Trkulja
AuthorIva Butić
AuthorIvo Ivić
AuthorVjekoslav Krželj
AuthorMarija Tonkić
AuthorMarija Hegeduš Jungvirth
AuthorMarina Payerl Pal
AuthorGoran Tešović
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Infectious Diseases)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Pharmacology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Infectology
Abstract (english)
Objectives: Rotavirus is the major cause of severe diarrhea in young children worldwide. In countries like Croatia, where rotavirus vaccine has not been introduced in the national immunization program, prospective surveillance is necessary to establish the diversity of rotavirus strains. The aim of this study was to describe the prevalence and geographical distribution of rotavirus strains in Croatia and to detect the possible emergence of novel strains. ----- Methods: The study was conducted among children ≤5 years of age with acute gastroenteritis at three hospitals located in different geographical regions of Croatia, during the years 2012 to 2014. Rotavirus was detected in stools using an immunochromatographic assay and then sent for further molecular analysis. ----- Results: Genotyping of 822 rotaviruses showed that the predominant circulating strain was G1P[8] (61.9%), followed by G2P[4] (19.5%), G1P[4] (3.9%), and G3P[8] (2.9%). A high prevalence of reassortants among common human rotavirus genotypes was detected (7.7%). Possible zoonotic reassortants were found, including G8 and G6 strains. The latter is described for the first time in Croatia. ----- Conclusions: This study represents pre-vaccination data that are important for decisions regarding immunization strategies in Croatia. The high prevalence of 'common' rotavirus strains circulating in Croatia may advocate for rotavirus vaccine introduction, but further surveillance is necessary to monitor the possible emergence of novel genotypes.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleInternational Journal of Infectious Diseases
Numberingvol. 89, pp. 3-9
p-ISSN1201-9712
e-ISSN1878-3511
DOIhttps://doi.org/10.1016/j.ijid.2019.09.008
URN:NBNurn:nbn:hr:105:477113
Publication2019-12
Document URLhttps://linkinghub.elsevier.com/retrieve/pii/S1201971219303704
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2021-03-09 08:39:23