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Scientific paper - Review paper
The Role of Mesenchymal Stem Cells in Atherosclerosis: Prospects for Therapy via the Modulation of Inflammatory Milieu
Journal of Clinical Medicine, 8 (2019), 9; 1413. https://doi.org/10.3390/jcm8091413
Mahdavi Gorabi, Armita; Banach, Maciej; Reiner, Željko; Pirro, Matteo; Hajighasemi, Saeideh; Johnston, Thomas P.; Sahebkar, Amirhossein

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Mahdavi Gorabi, A., Banach, M., Reiner, Ž., Pirro, M., Hajighasemi, S., Johnston, T. P. & Sahebkar, A. (2019). The Role of Mesenchymal Stem Cells in Atherosclerosis: Prospects for Therapy via the Modulation of Inflammatory Milieu. Journal of Clinical Medicine, 8. (9). doi: 10.3390/jcm8091413

Mahdavi Gorabi, Armita, et al. "The Role of Mesenchymal Stem Cells in Atherosclerosis: Prospects for Therapy via the Modulation of Inflammatory Milieu." Journal of Clinical Medicine, vol. 8, no. 9, 2019. https://doi.org/10.3390/jcm8091413

Mahdavi Gorabi, Armita, Maciej Banach, Željko Reiner, Matteo Pirro, Saeideh Hajighasemi, Thomas P. Johnston and Amirhossein Sahebkar. "The Role of Mesenchymal Stem Cells in Atherosclerosis: Prospects for Therapy via the Modulation of Inflammatory Milieu." Journal of Clinical Medicine 8, no. 9 (2019). https://doi.org/10.3390/jcm8091413

Mahdavi Gorabi, A., et al. (2019) 'The Role of Mesenchymal Stem Cells in Atherosclerosis: Prospects for Therapy via the Modulation of Inflammatory Milieu', Journal of Clinical Medicine, 8(9). doi: 10.3390/jcm8091413

Mahdavi Gorabi A, Banach M, Reiner Ž, Pirro M, Hajighasemi S, Johnston TP, and sur.. The Role of Mesenchymal Stem Cells in Atherosclerosis: Prospects for Therapy via the Modulation of Inflammatory Milieu. Journal of Clinical Medicine [Internet]. 2019 September 08 [cited 2024 December 25];8(9). doi: 10.3390/jcm8091413

A. Mahdavi Gorabi, et al., "The Role of Mesenchymal Stem Cells in Atherosclerosis: Prospects for Therapy via the Modulation of Inflammatory Milieu", Journal of Clinical Medicine, vol. 8, no. 9, September 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:141024. [Accessed: 25 December 2024]

Metadata
Title (english)The Role of Mesenchymal Stem Cells in Atherosclerosis: Prospects for Therapy via the Modulation of Inflammatory Milieu
AuthorArmita Mahdavi Gorabi
AuthorMaciej Banach
AuthorŽeljko Reiner
AuthorMatteo Pirro
AuthorSaeideh Hajighasemi
AuthorThomas P. Johnston
AuthorAmirhossein Sahebkar
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Atherosclerosis is a chronic, inflammatory disease that mainly affects the arterial intima. The disease is more prevalent in middle-age and older individuals with one or more cardiovascular risk factors, including dyslipidemia, hypertension, diabetes, smoking, obesity, and others. The beginning and development of atherosclerosis has been associated with several immune components, including infiltration of inflammatory cells, monocyte/macrophage-derived foam cells, and inflammatory cytokines and chemokines. Mesenchymal stem cells (MSCs) originate from several tissue sources of the body and have self-renewal and multipotent differentiation characteristics. They also have immunomodulatory and anti-inflammatory properties. Recently, it was shown that MSCs have a regulatory role in plasma lipid levels. In addition, MSCs have shown to have promising potential in terms of treatment strategies for several diseases, including those with an inflammatory component. In this regard, transplantation of MSCs to patients with atherosclerosis has been proposed as a novel strategy in the treatment of this disease. In this review, we summarize the current advancements regarding MSCs for the treatment of atherosclerosis.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleJournal of Clinical Medicine
Numberingvol. 8, no. 9, 1413
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm8091413
URN:NBNurn:nbn:hr:105:141024
Publication2019-09-08
Document URLhttps://www.mdpi.com/2077-0383/8/9/1413
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2021-03-09 08:52:48