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master's thesis
Prenatalna dijagnostika i praćenje fetalnih srčanih grešaka
Zagreb: University of Zagreb, School of Medicine, 2020. urn:nbn:hr:105:100876
Galić, Iva
University of Zagreb
School of Medicine
Department of Gynecology and Obstetrics

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Galić, I. (2020). Prenatalna dijagnostika i praćenje fetalnih srčanih grešaka (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:100876

Galić, Iva. "Prenatalna dijagnostika i praćenje fetalnih srčanih grešaka." Master's thesis, University of Zagreb, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:105:100876

Galić, Iva. "Prenatalna dijagnostika i praćenje fetalnih srčanih grešaka." Master's thesis, University of Zagreb, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:105:100876

Galić, I. (2020). 'Prenatalna dijagnostika i praćenje fetalnih srčanih grešaka', Master's thesis, University of Zagreb, School of Medicine, accessed 25 July 2024, https://urn.nsk.hr/urn:nbn:hr:105:100876

Galić I. Prenatalna dijagnostika i praćenje fetalnih srčanih grešaka [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2020 [cited 2024 July 25] Available at: https://urn.nsk.hr/urn:nbn:hr:105:100876

I. Galić, "Prenatalna dijagnostika i praćenje fetalnih srčanih grešaka", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:105:100876

Metadata
TitlePrenatalna dijagnostika i praćenje fetalnih srčanih grešaka
Title (english)Prenatal diagnosis and follow-up of fetal cardiac anomalies
AuthorIva Galić
MentorBerivoj Mišković (mentor)
Committee memberVesna Elveđi Gašparović (predsjednik povjerenstva)
Committee memberDinka Pavičić Baldani (član povjerenstva)
Committee memberBerivoj Mišković (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Gynecology and Obstetrics)
Zagreb
Defense date and country2020-07-17, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract
Prirođene srčane greške (PSG) najčešći su uzrok smrti u perinatalnom i dojenačkom razdoblju. U Hrvatskoj 7, 2 promila djece ima PSG-u. Clark je prema etiopatogenetskim kriterijima PSG razvrstao u šest skupina. Fetalna cirkulacija je specifična, a glavno obilježlje je postojanje tri shunta na razini ductus venosus, foramen ovale i ductus Botalli. Isto tako, fetalno srce ima složenu morfološku strukturu te je zbog toga za prenatalnu dijagnostiku PSG-a potrebno adekvatno poznavanje navedenih specifičnosti fetalnog srca. Etiologija PSG-a je multifaktorska, a najčešće se upotrebljava funkcionalna klasifikacija. Prema tim se kriterijima PSG dijele u tri skupine: greške s početnim lijevo – desnim pretokom krvi, greške s početnim desno – lijevim pretokom krvi te greške u kojima je prisutna opstrukcija bez cijanoze. Fetalna ehokardiografija (FE) ima najvažnju ulogu u dijagnostici PSG-a. Najčešća je indikacija za FE-u sumnja na strukturnu abnormalnost fetalnog srca. Ona omogućuje adekvatan nadzor trudnoće, planiranje vremena i načina porođaja te adekvatno zbrinavanje i rano liječenje novorođenčeta. S napretkom FE-e unatrag nekoliko godina neke srčane greške liječe se in utero. Riječ je o intervencijskoj kataterizaciji in utero koja omogućava liječenje aortalne stenoze (AS) s razvijajućim sindromom hipoplastičnog lijevog srca (HLHS), HLHS-a s intaktnim atrijskim septumom, dilatiranog LV-a s teškom mitralnom regurgitacijom i AS-om te pulmonalne atrezije (PA) s intaktnim ventrikularnim septumom. Planirani porod u visoko specijaliziranim centrima ključna je stavka za optimalan ishod djece s PSG-a.
Abstract (english)
Congenital heart defects (CHD) are the most common cause of death in the perinatal and infantile period. In Croatia, 7,2 out of 1000 children are born with CHD. Based on ethiopathogenic criteria, Clark has divided CHD into six groups. The main features of fetal circulation are three shunts that occur at ductus venosus, foramen ovale and ductus Botalli. Fetal heart is morphologically immensely complex and, therefore, thorough understanding of morphology is required for perinatal diagnosis of CHD. Etiology of CHD is multifactorial and functional classification is most commonly used. By these criteria CHD are divided into three groups: defects with initial left to right blood flow, defects with initial right to left blood flow, and obstructive defects that present without cyanosis. Fetal echocardiography has a major role in CHD diagnosis. The most common indication for FE is a suspected structural heart abnormality. FE provides adequate pregnancy monitoring, delivery planning, neonatal care and treatment. With rapid improvement of FE in the past years, it has become possible to treat some CHD in utero. Catheter intervention in utero enables treatment of aortic stenosis (AS) with developing hypoplastic left heart syndrome (HLHS), HLHS with intact atrial septum, dilated LV with severe mitral regurgitation and AS, and pulmonary atresia (PA) with intact ventricular septum. Planned delivery in highly specialized centers is a crucial element for a favorable outcome of CHD.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:100876
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-03-17 10:23:50