Alzheimer’s disease is characterized by progressive dementia and memory loss, caused by the formation of amyloid plaques and neurofibrillary tangles in the brain, particularly in the cerebral cortex and hippocampus. The prevalence increases sharply with age and over time changes in the brain lead to progressive neuronal loss. AD refers to dementia that occurs gradually in adulthood and may be followed by earlier brain damage, but often has no known cause. Common symptoms of AD are problems with concentration and short-term memory, spatio-temporal disorientation, apathy and depression. The moderate / severe phase of Alzheimer's dementia is marked by a progressive decline in cognitive function, resulting in more severe functional impairment and increasing dependence on others in daily life activities. Studies in recent years have revealed specific genetic and molecular mechanisms responsible for the development of AD. This progress raised hopes for more effective treatment, but success proved unattainable, partly because many factors contribute to the development of the disease and because symptoms of the disease become apparent only after the underlying pathology has already progressed. Today’s approved drugs have little effect on dementia, especially AD, and are unable to stop disease progression. Therefore, the identification and application of non-pharmacological and preventive strategies seems to be more practical and crucial to combat this disease. The non-pharmacological approach is slowly evolving and often includes various forms of psychosocial therapy such as art therapy, music, dance and drama therapy and many others. Patients can express themselves through artistic approach using non-verbal communication and thus express their negative emotions and improve social skills, which ultimately contributes to improving cognitive abilities and reducing behavioral and psychological symptoms, and significantly improves the quality of patiens life.