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master's thesis
Kirurško liječenje tumora karotidnog tjelešca
Zagreb: University of Zagreb, School of Medicine, 2020. urn:nbn:hr:105:014602
Hriberski, Klaudija
University of Zagreb
School of Medicine
Department of Surgery

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Hriberski, K. (2020). Kirurško liječenje tumora karotidnog tjelešca (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:014602

Hriberski, Klaudija. "Kirurško liječenje tumora karotidnog tjelešca." Master's thesis, University of Zagreb, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:105:014602

Hriberski, Klaudija. "Kirurško liječenje tumora karotidnog tjelešca." Master's thesis, University of Zagreb, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:105:014602

Hriberski, K. (2020). 'Kirurško liječenje tumora karotidnog tjelešca', Master's thesis, University of Zagreb, School of Medicine, accessed 29 April 2024, https://urn.nsk.hr/urn:nbn:hr:105:014602

Hriberski K. Kirurško liječenje tumora karotidnog tjelešca [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2020 [cited 2024 April 29] Available at: https://urn.nsk.hr/urn:nbn:hr:105:014602

K. Hriberski, "Kirurško liječenje tumora karotidnog tjelešca", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:105:014602

Metadata
TitleKirurško liječenje tumora karotidnog tjelešca
Title (english)Surgical treatment of carotid body tumors
AuthorKlaudija Hriberski
MentorPredrag Pavić (mentor)
Committee memberTomislav Luetić (predsjednik povjerenstva)
Committee memberTomislav Meštrović (član povjerenstva)
Committee memberPredrag Pavić (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Surgery)
Zagreb
Defense date and country2020-07-17, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Abstract
Karotidno tjelešce kemoreceptorski je organ smješten u adventiciji karotidne bifurkacije, odgovoran za održavanje homeostaze pO2, pCO2 i pH. Tumori karotidnog tjelešca pripadaju skupini rijetkih tumora i mogu se podijeliti na tri tipa; sporadični, obiteljski i hiperplastični. Najčešće se očituju kao bezbolne tvorbe na lateralnoj strani vrata, koje u uznapredovaloj fazi mogu uzrokovati neurološke simptome i simptome lokalne kompresije. Temelj dijagnostike je ultrazvuk, a CTA, MRA i DSA koriste se u prijeoperacijskoj obradi. Shamblinova klasifikacije dijeli tumore u tri skupine na temelju odnosa tumora s karotidnim arterijama. Zlatni standard liječenja je subadventicijska resekcija; radioterapija i opservacija alternativne su opcije. Kirurška resekcija danas je praćena niskim mortalitetom, ali još uvijek se veže uz značajan rizik neurovaskularne ozljede. Uspješnost operacije može se potencirati primjenom prijeoperacijske devaskularizacije putem embolizacije, ugradnje stenta ili prijeoperacijske radioterapije.
Abstract (english)
The carotid body is a chemoreceptor organ found in adventitia of carotid bifurcation responsible for maintaining homeostatis of pO2, pCO2 i pH. Carotid body tumors belong to the group of rare tumors and can be divided into three types: sporadic, familial and hyperplastic. They most often present as painless mass on the lateral side of the neck and can, in advanced stages, cause neurological symptoms and symptoms of local compression. The base for diagnosis is ultrasound,while CT, MR and angiography are used in preoperative assesment. Shamblin's classification divides these tumors into three groups based on the relationship of the tumor to the carotid arteries. The gold standard of treatment is subadventricular resection; radiotherapy and observation are alternative options. Surgical resection today is accompanied with low mortality, but is still associated with a significant risk of neurovascular injury. The success of the operation can be enhanced by preoperative devascularization, stent implantation or preoperative radiotherapy.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:014602
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-03-26 13:09:28