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master's thesis
Izazovi sestrinstva u skrbi za bolesnika liječenog CAR-T stanicama
Zagreb: University of Zagreb, School of Medicine, 2020. urn:nbn:hr:105:407368
Družinić, Vesna
University of Zagreb
School of Medicine
Department of Internal Medicine

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Družinić, V. (2020). Izazovi sestrinstva u skrbi za bolesnika liječenog CAR-T stanicama (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:407368

Družinić, Vesna. "Izazovi sestrinstva u skrbi za bolesnika liječenog CAR-T stanicama." Master's thesis, University of Zagreb, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:105:407368

Družinić, Vesna. "Izazovi sestrinstva u skrbi za bolesnika liječenog CAR-T stanicama." Master's thesis, University of Zagreb, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:105:407368

Družinić, V. (2020). 'Izazovi sestrinstva u skrbi za bolesnika liječenog CAR-T stanicama', Master's thesis, University of Zagreb, School of Medicine, accessed 24 December 2024, https://urn.nsk.hr/urn:nbn:hr:105:407368

Družinić V. Izazovi sestrinstva u skrbi za bolesnika liječenog CAR-T stanicama [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2020 [cited 2024 December 24] Available at: https://urn.nsk.hr/urn:nbn:hr:105:407368

V. Družinić, "Izazovi sestrinstva u skrbi za bolesnika liječenog CAR-T stanicama", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:105:407368

Metadata
TitleIzazovi sestrinstva u skrbi za bolesnika liječenog CAR-T stanicama
Title (english)Challenges for nurses caring for patients treated with CAR T cells
AuthorVesna Družinić
MentorIgor Aurer (mentor)
Committee memberJasenka Markeljević (predsjednik povjerenstva)
Committee memberRadovan Vrhovac (član povjerenstva)
Committee memberIgor Aurer (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Zagreb
Defense date and country2020-07-20, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
Terapija lijekom tisagenlekleucel, odnosno primjena T limfocita s kimeričnim receptorom za antigen, CAR–T stanice, pruža novu priliku bolesnicima s određenim tipovima uznapredovale, refraktorne ili recidivirajuće akutne limfoblastične leukemije i B-velikostaničnog limfoma, a pred medicinske sestre odjela na kome se liječe postavlja brojne izazove. Iako medicinske sestre koje se skrbe za hematološke bolesnike liječene kemoterapijom i transplantacijom koštane srži imaju znanje, vještine i kompetencije da pruže sveobuhvatnu skrb bolesnicima koji primaju CAR-T staničnu terapiju, moraju proći obuku za procjenu i ublažavanje rizika (REMS), kako bi zadovoljile zahtjeve koji se pred njih postavljaju. Nova terapija s jedinstvenim nuspojavama, potrebama za procjenom i dokumentiranjem stanja bolesnika, postupak primjene infuzije CAR-T stanica, edukacija pacijenta, obitelji ili skrbnika, brzo prepoznavanje hitnih stanja kod bolesnika, sve su to izazovi s kojima se susrećemo u skrbi za bolesnika liječenog CAR-T stanicama. Izrada jedinstvene sestrinske dokumentacije za praćenje nuspojava liječenja je jedan od ključnih sestrinskih izazova koji je omogućio izradu kvalitetnog plana sestrinske skrbi. Kvalitetnim odgovorom na ove izazove medicinske sestre imaju jednu od ključnih uloga u ishodu liječenja bolesnika CAR-T stanicama. Možemo reći da izazovi u skrbi za bolesnika liječenog CAR-T stanicama za medicinske sestre predstavljaju umijeće sadašnjosti i veliki izazov u budućnosti.
Abstract (english)
Treatment with the drug tisagenlecleucel, i.e. CAR–T cells, offers a new opportunity to patients with certain types of advanced, refractory or relapsing acute lymphoblastic leukemia and B-large cell lymphoma and poses multiple challenges to nurses working on units where these patients are treated. Despite the fact that nurses caring for hematological patients treated with chemotherapy and bone marrow transplantation have knowledge, skills and competencies to offer comprehensive care to patients receiving CAR-T cell therapy, they have to be trained in risk evaluation and mitigation strategies (REMS) in order to fulfill the demands placed before them. This new therapy with unique side-effects, needs for assessment and documentation of patient's condition, CAR-T cell infusion procedure, education of patients, their families and caregivers, rapid recognition of medical emergencies in patients, are all challenges we face in caring for patients treated with CAR-T cells. Creation of a unique nursing documentation for follow-up of side-effects is one of the main challenges enabling the creation of a good nursing care plan. We are therefore justified in stating that challenges in care for CAR-T cells treated patients represent nursing skills of present and major challenges of the future.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:407368
Study programmeTitle: Studies in Nursing
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-05-10 10:00:39