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master's thesis
Učestalost i raspodjela okultnih regionalnih metastaza kod tumora žlijezda slinovnica
Zagreb: University of Zagreb, School of Medicine, 2020. urn:nbn:hr:105:063496
Matoc, Lovro
University of Zagreb
School of Medicine
Department of Maxillofacial Surgery and Dentistry

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Matoc, L. (2020). Učestalost i raspodjela okultnih regionalnih metastaza kod tumora žlijezda slinovnica (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:063496

Matoc, Lovro. "Učestalost i raspodjela okultnih regionalnih metastaza kod tumora žlijezda slinovnica." Master's thesis, University of Zagreb, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:105:063496

Matoc, Lovro. "Učestalost i raspodjela okultnih regionalnih metastaza kod tumora žlijezda slinovnica." Master's thesis, University of Zagreb, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:105:063496

Matoc, L. (2020). 'Učestalost i raspodjela okultnih regionalnih metastaza kod tumora žlijezda slinovnica', Master's thesis, University of Zagreb, School of Medicine, accessed 26 November 2024, https://urn.nsk.hr/urn:nbn:hr:105:063496

Matoc L. Učestalost i raspodjela okultnih regionalnih metastaza kod tumora žlijezda slinovnica [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2020 [cited 2024 November 26] Available at: https://urn.nsk.hr/urn:nbn:hr:105:063496

L. Matoc, "Učestalost i raspodjela okultnih regionalnih metastaza kod tumora žlijezda slinovnica", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:105:063496

Metadata
TitleUčestalost i raspodjela okultnih regionalnih metastaza kod tumora žlijezda slinovnica
Title (english)Incidence and distribution of occult regional metastases in salivary gland tumors
AuthorLovro Matoc
MentorIvica Lukšić (mentor)
Committee memberMartin Jurlina (predsjednik povjerenstva)
Committee memberEmil Dediol (član povjerenstva)
Committee memberIvica Lukšić (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Maxillofacial Surgery and Dentistry)
Zagreb
Defense date and country2020-07-17, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Oncology
Abstract
Tumori žlijezda slinovnica su vrlo rijetka i raznolika skupina tumora glave i vrata. Najčešće se javljaju u parotidnoj žlijezdi, malim žlijezdama slinovnicama i submandibularnoj žlijezdi. Tumori žlijezda slinovnica najčešće su benigni i smješteni u parotidnoj žlijezdi. Najčešći benigni tumor je pleomorfni adenom, a zloćudni mukoepidermoidni karcinom. Glavni put metastaziranja je u regionalne limfne čvorove vrata. Regionalne metastaze, anatomska lokalizacija tumora i tumorska histologija važni su prognostički čimbenici. Liječenje primarnog tumora uključuje kompletnu kiruršku eksciziju s urednim rubovima i disekciju vrata ovisnu o cN i lokalizaciji primarnog tumora. Opravdanost elektivne disekcije upitna je zbog male učestalosti okultnih regionalnih metastaza. Cilj ovog retrospektivnog istraživanja bio je utvrditi učestalost i raspodjelu okultnih regionalnih metastaza kod bolesnika sa zloćudnim tumorima žlijezda slinovnica. Istraživanje je obuhvatilo 33 bolesnika s histološki potvrđenim zloćudnim tumorom u razdoblju od gotovo 10 godina (2010. – 2019.). Prema rezultatima ovog istraživanja, učestalost okultnih regionalnih metastaza bila je 3,03%. Zloćudni tumori submandibularne žlijezde najčešće su regionalno metastazirali. Najčešća lokalizacija okultnih regionalnih metastaza bila je regija I vrata.
Abstract (english)
Salivary gland tumors are very rare and diverse group of head and neck tumors. They most commonly appear in parotid gland, small salivary glands and submandibular gland. Salivary gland tumors are generally benign and localized in parotid gland. The most common benign tumor is pleomorphic adenoma, and the most common malignant tumor is mucoepidermoid carcinoma. The main metastatic pathway is in the regional lymph nodes of the neck. Regional metastasis, tumor localization and histology are important prognostic factors. The managing of primary tumor includes a complete surgical excision with free margins and a neck dissection dependent on cN and localization of primary tumor. Justification for elective neck dissection is questionable due to low frequency of occult regional metastasis. The goal of this retrospective study was to determine the frequency and distribution of occult regional metastasis in patients with salivary gland tumors. This retrospective study included 33 patients with histologically verified malignant tumors during a period of almost 10 years (2010. – 2019.). According to the results of this study, the frequency of regional occult metastasis was 3.03%. Malignant tumors of submandibular gland most frequently metastasized. The most frequent localization of regional occult metastasis was in region I of the neck.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:063496
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-09-01 09:13:38