prikaz prve stranice dokumenta The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report
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Scientific paper - Case study
The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report
Croatian Medical Journal, 62 (2021), 4; 411-419. https://doi.org/10.3325/cmj.2021.62.411
Radoš, Milan; Orešković, Darko; Klarica, Marijan

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Radoš, M., Orešković, D. & Klarica, M. (2021). The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report. Croatian Medical Journal, 62. (4), 411-419. doi: 10.3325/cmj.2021.62.411

Radoš, Milan, et al. "The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report." Croatian Medical Journal, vol. 62, no. 4, 2021, pp. 411-419. https://doi.org/10.3325/cmj.2021.62.411

Radoš, Milan, Darko Orešković and Marijan Klarica. "The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report." Croatian Medical Journal 62, no. 4 (2021): 411-419. https://doi.org/10.3325/cmj.2021.62.411

Radoš, M., Orešković, D. and Klarica, M. (2021) 'The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report', Croatian Medical Journal, 62(4), pp. 411-419. doi: 10.3325/cmj.2021.62.411

Radoš M, Orešković D, Klarica M. The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report. Croatian Medical Journal [Internet]. 2021 August 31 [cited 2024 December 30];62(4):411-419. doi: 10.3325/cmj.2021.62.411

M. Radoš, D. Orešković and M. Klarica, "The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report", Croatian Medical Journal, vol. 62, no. 4, pp. 411-419, August 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:469454. [Accessed: 30 December 2024]

Metadata
Title (english)The role of mesencephalic aqueduct obstruction in hydrocephalus development: a case report
AuthorMilan Radoš
AuthorDarko Orešković
AuthorMarijan Klarica
Author's institutionUniversity of Zagreb
School of Medicine
(Croatian Institiute for Brain Research)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Pharmacology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Neuroscience
Abstract (english)
We report on three patients with mesencephalic aqueduct obstruction, which completely blocked the cerebrospinal fluid communication between the third and fourth cerebral ventricle, demonstrated by standard and high-resolution magnetic resonance sequences. Only one patient developed radiological and clinical presentation of hydrocephalus, without radiological signs of increased intraventricular pressure. The remaining two patients did not show clinical signs of hydrocephalus and had a normal radiological presentation of the ventricular system. These findings contradict the classical concept of cerebrospinal fluid physiology. This concept assumes a unidirectional circulation of cerebrospinal fluid through the mesencephalic aqueduct from the secretion site, predominantly in the choroid plexuses, to the resorption site, predominantly in the dural venous sinuses. Therefore, the obstruction of the mesencephalic aqueduct would inevitably lead to triventricular hypertensive hydrocephalus in all patients. The current observations, however, accord with the new concept of cerebrospinal fluid physiology, which postulates that cerebrospinal fluid does not circulate unidirectionally because it is both formed and resorbed along the entire capillary network within the central nervous system.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian Medical Journal
Numberingvol. 62, no. 4, pp. 411-419
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2021.62.411
URN:NBNurn:nbn:hr:105:469454
Publication2021-08-31
Document URLhttp://www.cmj.hr/2021/62/4/34472744.htm
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2021-09-21 08:41:08