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Scientific paper - Original scientific paper
Effects of Environmental Factors on Severity and Mortality of COVID-19
Frontiers in Medicine, 7 (2021); 607786. https://doi.org/10.3389/fmed.2020.607786
Kifer, Domagoj; Bugada, Dario; Villar-Garcia, Judit; Gudelj, Ivan; Menni, Cristina; Sudre, Carole; Vučković, Frano; Ugrina, Ivo; Lorini, Luca F.; Posso, Margarita; Bettinelli, Silvia; Ughi, Nicola; Maloberti, Alessandro; Epis, Oscar; Giannattasio, Cristina; Rossetti, Claudio; Kalogjera, Livije; Peršec, Jasminka; Ollivere, Luke; Ollivere, Benjamin J.; Yan, Huadong; Cai, Ting; Aithal, Guruprasad P.; Steves, Claire J.; Kantele, Anu; Kajova, Mikael; Vapalahti, Olli; Sajantila, Antti; Wojtowicz, Rafal; Wierzba, Waldemar; Krol, Zbigniew; Zaczynski, Artur; Zycinska, Katarina; Postula, Marek; Lukšić, Ivica; Čivljak, Rok; Markotić, Alemka; Brachmann, Johannes; Markl, Andreas; Mahnkopf, Christian; Murray, Benjamin; Ourselin, Sebastien; Valdes, Ana M.; Horcajada, Juan P.; Castells, Xavier; Pascual, Julio; Allegri, Massimo; Primorac, Dragan; Spector, Tim D.; Barrios, Clara; Lauc, Gordan More authors...

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Kifer, D., Bugada, D., Villar Garcia, J., Gudelj, I., Menni, C., Sudre, C. ... Lauc, G. (2021). Effects of Environmental Factors on Severity and Mortality of COVID-19. Frontiers in Medicine, 7.. doi: 10.3389/fmed.2020.607786

Kifer, Domagoj, et al. "Effects of Environmental Factors on Severity and Mortality of COVID-19." Frontiers in Medicine, vol. 7, 2021. https://doi.org/10.3389/fmed.2020.607786

Kifer, Domagoj, Dario Bugada, Judit Villar Garcia, Ivan Gudelj, Cristina Menni, Carole Sudre, Frano Vučković, et al. "Effects of Environmental Factors on Severity and Mortality of COVID-19." Frontiers in Medicine 7 (2021). https://doi.org/10.3389/fmed.2020.607786

Kifer, D., et al. (2021) 'Effects of Environmental Factors on Severity and Mortality of COVID-19', Frontiers in Medicine, 7. doi: 10.3389/fmed.2020.607786

Kifer D, Bugada D, Villar Garcia J, Gudelj I, Menni C, Sudre C, and sur.. Effects of Environmental Factors on Severity and Mortality of COVID-19. Frontiers in Medicine [Internet]. 2021 January 20 [cited 2024 December 25];7. doi: 10.3389/fmed.2020.607786

D. Kifer, et al., "Effects of Environmental Factors on Severity and Mortality of COVID-19", Frontiers in Medicine, vol. 7, January 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:593227. [Accessed: 25 December 2024]

Metadata
Title (english)Effects of Environmental Factors on Severity and Mortality of COVID-19
AuthorDomagoj Kifer
AuthorDario Bugada
AuthorJudit Villar-Garcia
AuthorIvan Gudelj
AuthorCristina Menni
AuthorCarole Sudre
AuthorFrano Vučković
AuthorIvo Ugrina
AuthorLuca F. Lorini
AuthorMargarita Posso
AuthorSilvia Bettinelli
AuthorNicola Ughi
AuthorAlessandro Maloberti
AuthorOscar Epis
AuthorCristina Giannattasio
AuthorClaudio Rossetti
AuthorLivije Kalogjera
AuthorJasminka Peršec
AuthorLuke Ollivere
AuthorBenjamin J. Ollivere
AuthorHuadong Yan
AuthorTing Cai
AuthorGuruprasad P. Aithal
AuthorClaire J. Steves
AuthorAnu Kantele
AuthorMikael Kajova
AuthorOlli Vapalahti
AuthorAntti Sajantila
AuthorRafal Wojtowicz
AuthorWaldemar Wierzba
AuthorZbigniew Krol
AuthorArtur Zaczynski
AuthorKatarina Zycinska
AuthorMarek Postula
AuthorIvica Lukšić
AuthorRok Čivljak
AuthorAlemka Markotić
AuthorJohannes Brachmann
AuthorAndreas Markl
AuthorChristian Mahnkopf
AuthorBenjamin Murray
AuthorSebastien Ourselin
AuthorAna M. Valdes
AuthorJuan P. Horcajada
AuthorXavier Castells
AuthorJulio Pascual
AuthorMassimo Allegri
AuthorDragan Primorac
AuthorTim D. Spector
AuthorClara Barrios
AuthorGordan Lauc
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Infectious Diseases)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Maxillofacial Surgery and Dentistry)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Othorhinolaryngology and Head and Neck Surgery)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Otorhinolaryngology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Infectology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Abstract (english)
Background: Most respiratory viruses show pronounced seasonality, but for SARS-CoV-2, this still needs to be documented. ----- Methods: We examined the disease progression of COVID-19 in 6,914 patients admitted to hospitals in Europe and China. In addition, we evaluated progress of disease symptoms in 37,187 individuals reporting symptoms into the COVID Symptom Study application. ----- Findings: Meta-analysis of the mortality risk in seven European hospitals estimated odds ratios per 1-day increase in the admission date to be 0.981 (0.973-0.988, p < 0.001) and per increase in ambient temperature of 1°C to be 0.854 (0.773-0.944, p = 0.007). Statistically significant decreases of comparable magnitude in median hospital stay, probability of transfer to the intensive care unit, and need for mechanical ventilation were also observed in most, but not all hospitals. The analysis of individually reported symptoms of 37,187 individuals in the UK also showed the decrease in symptom duration and disease severity with time. ----- Interpretation: Severity of COVID-19 in Europe decreased significantly between March and May and the seasonality of COVID-19 is the most likely explanation.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleFrontiers in Medicine
Numberingvol. 7, 607786
e-ISSN2296-858X
DOIhttps://doi.org/10.3389/fmed.2020.607786
URN:NBNurn:nbn:hr:105:593227
Publication2021-01-20
Document URLhttps://www.frontiersin.org/articles/10.3389/fmed.2020.607786/full
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2021-09-24 09:02:14