prikaz prve stranice dokumenta The effects of omega-3 fatty acids supplementation on metabolic status in pregnant women: a systematic review and meta-analysis of randomized controlled trials
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Scientific paper - Review paper
The effects of omega-3 fatty acids supplementation on metabolic status in pregnant women: a systematic review and meta-analysis of randomized controlled trials
Journal of Diabetes & Metabolic Disorders, 19 (2020), 2; 1685-1699. https://doi.org/10.1007/s40200-020-00558-5
Amirani, Elaheh; Asemi, Zatollah; Asbaghi, Omid; Milajerdi, Alireza; Reiner, Željko; Mansournia, Mohammad Ali; Hallajzadeh, Jamal; Moazzami, Bahram; Chaichian, Shahla

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Amirani, E., Asemi, Z., Asbaghi, O., Milajerdi, A., Reiner, Ž., Mansournia, M. A. ... Chaichian, S. (2020). The effects of omega-3 fatty acids supplementation on metabolic status in pregnant women: a systematic review and meta-analysis of randomized controlled trials. Journal of Diabetes & Metabolic Disorders, 19. (2), 1685-1699. doi: 10.1007/s40200-020-00558-5

Amirani, Elaheh, et al. "The effects of omega-3 fatty acids supplementation on metabolic status in pregnant women: a systematic review and meta-analysis of randomized controlled trials." Journal of Diabetes & Metabolic Disorders, vol. 19, no. 2, 2020, pp. 1685-1699. https://doi.org/10.1007/s40200-020-00558-5

Amirani, Elaheh, Zatollah Asemi, Omid Asbaghi, Alireza Milajerdi, Željko Reiner, Mohammad Ali Mansournia, Jamal Hallajzadeh, Bahram Moazzami and Shahla Chaichian. "The effects of omega-3 fatty acids supplementation on metabolic status in pregnant women: a systematic review and meta-analysis of randomized controlled trials." Journal of Diabetes & Metabolic Disorders 19, no. 2 (2020): 1685-1699. https://doi.org/10.1007/s40200-020-00558-5

Amirani, E., et al. (2020) 'The effects of omega-3 fatty acids supplementation on metabolic status in pregnant women: a systematic review and meta-analysis of randomized controlled trials', Journal of Diabetes & Metabolic Disorders, 19(2), pp. 1685-1699. doi: 10.1007/s40200-020-00558-5

Amirani E, Asemi Z, Asbaghi O, Milajerdi A, Reiner Ž, Mansournia MA, and sur.. The effects of omega-3 fatty acids supplementation on metabolic status in pregnant women: a systematic review and meta-analysis of randomized controlled trials. Journal of Diabetes & Metabolic Disorders [Internet]. 2020 June 06 [cited 2024 November 07];19(2):1685-1699. doi: 10.1007/s40200-020-00558-5

E. Amirani, et al., "The effects of omega-3 fatty acids supplementation on metabolic status in pregnant women: a systematic review and meta-analysis of randomized controlled trials", Journal of Diabetes & Metabolic Disorders, vol. 19, no. 2, pp. 1685-1699, June 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:694264. [Accessed: 07 November 2024]

Metadata
Title (english)The effects of omega-3 fatty acids supplementation on metabolic status in pregnant women: a systematic review and meta-analysis of randomized controlled trials
AuthorElaheh Amirani
AuthorZatollah Asemi
AuthorOmid Asbaghi
AuthorAlireza Milajerdi
AuthorŽeljko Reiner
AuthorMohammad Ali Mansournia
AuthorJamal Hallajzadeh
AuthorBahram Moazzami
AuthorShahla Chaichian
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Background and objective: Data regarding the effects of omega-3 polyunsaturated fatty acids (PUFA) supplementation on metabolic status of pregnant women are limited. This systematic review and meta-analysis were done based on randomized controlled trials (RCTs) dealing with the effects of omega-3 PUFA supplementation on glycemic control, lipoproteins, inflammation and oxidative stress in pregnant women. ------ Methods: Following databases were searched for eligible studies published from inception to until 2019: MEDLINE, EMBASE, Web of Science, PubMed, Scopus, Cochrane Library, and Google scholar. Studies that evaluated the effect of omega-3 PUFA supplementation on parameters of glycemic control, lipoproteins, inflammation and oxidative stress in pregnant women were found by using the key MeSH. A study quality assessment was performed using the Cochrane Collaboration risk of bias tool and heterogeneity between studies was statistically computed using Cochrane's Q test and I-square (I2). Data were pooled using a random-effects model and weighted mean difference (WMD) was considered as the overall effect size. ------ Results: No significant effects of omega-3 PUFA supplementation on FPG, insulin, insulin resistance, total cholesterol, triglycerides, LDL-cholesterol, total cholesterol/HDL-cholesterol, interleukin 6 (IL-6), IL-8, and malondialdehyde were found. However, omega-3 PUFA significantly increased serum concentrations of HDL-cholesterol (WMD: 3.10; 95% CI: 0.18, 6.03) and reduced C-reactive protein (WMD: -1.85; 95% CI: -2.61, -1.09). ------ Conclusion: Based on the results of this meta-analysis omega-3 PUFA supplementation during pregnancy has a significant beneficial effect on HDL-cholesterol, and C-reactive protein.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleJournal of Diabetes & Metabolic Disorders
Numberingvol. 19, no. 2, pp. 1685-1699
e-ISSN2251-6581
DOIhttps://doi.org/10.1007/s40200-020-00558-5
URN:NBNurn:nbn:hr:105:694264
Publication2020-06-06
Document URLhttps://link.springer.com/10.1007/s40200-020-00558-5
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2021-09-27 09:00:00