prikaz prve stranice dokumenta Platelet aggregation defects in women with endometriosis
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master's thesis
Platelet aggregation defects in women with endometriosis
Zagreb: University of Zagreb, School of Medicine, 2020. urn:nbn:hr:105:461318
Rahimy, Mohammad Omar
University of Zagreb
School of Medicine
Department of Gynecology and Obstetrics

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Rahimy, M. O. (2020). Platelet aggregation defects in women with endometriosis (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:461318

Rahimy, Mohammad Omar. "Platelet aggregation defects in women with endometriosis." Master's thesis, University of Zagreb, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:105:461318

Rahimy, Mohammad Omar. "Platelet aggregation defects in women with endometriosis." Master's thesis, University of Zagreb, School of Medicine, 2020. https://urn.nsk.hr/urn:nbn:hr:105:461318

Rahimy, M. O. (2020). 'Platelet aggregation defects in women with endometriosis', Master's thesis, University of Zagreb, School of Medicine, accessed 29 April 2024, https://urn.nsk.hr/urn:nbn:hr:105:461318

Rahimy MO. Platelet aggregation defects in women with endometriosis [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2020 [cited 2024 April 29] Available at: https://urn.nsk.hr/urn:nbn:hr:105:461318

M. O. Rahimy, "Platelet aggregation defects in women with endometriosis", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2020. Available at: https://urn.nsk.hr/urn:nbn:hr:105:461318

Metadata
TitlePlatelet aggregation defects in women with endometriosis
Title (croatian)Poremećaji agregacije trombocita u žena s endometriozom
AuthorMohammad Omar Rahimy
MentorLana Škrgatić (mentor)
Committee memberLana Škrgatić (predsjednik povjerenstva)
Committee memberMario Ćorić (član povjerenstva)
Committee memberDinka Pavičić Baldani (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Gynecology and Obstetrics)
Zagreb
Defense date and country2020-07-17, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract
Major progress has been seen in the past few decades in the management of gynecological conditions and obstetric care in women with bleeding disorders (BDs). However, there remain many ambiguous issues within the field. A sequence of observational studies was conducted to address these issues with a goal to improve patient care. In the recent findings showing that platelets play important roles in the development of endometriosis. Hence, this review was undertaken to see if there was a connection between bleeding disorders specially platelet aggregation defect and endometriosis. This association was explored in animal models as well as in clinical studies suggesting that women with endometriosis have a higher rate of platelet aggregation defect. Deficiency of von Willebrand factor (VWF), a protein required for the normal adhesion of platelets to the site of injured endothelium may be associated with advanced stage of endometriosis on laparoscopy. The present review concludes that platelets may be a culprit in the development of endometriosis and that platelet aggregation were seen in endometriotic lesions.
Abstract (croatian)
Posljednjih nekoliko desetljeća bilježimo veliki napredak u liječenju ginekoloških poremećaja i opstetričke skrbi u žena sa poremećajima koagulacije. Unatoč tome ostaje niz nerazriješenih pitanja u ovom području. Niz opservacijskih studija provedeno je radi rasvjetljavanja ove problematike s glavnim ciljem poboljšanja skrbi o bolesnicama. Nedavne studije pokazale su da trombociti igraju važnu ulogu u razvoju endometrioze. Cilj ovog preglednog rada bio je istražiti postoji li povezanost između između poremećaja koagulacije, posebice poremećaja agregacije trombocita i endometrioze. Ova je povezanost istraživana na životinjskim modelima kao i u kliničkim studijama koje ukazuju da žene s endometriozom imaju veću učestalost poremećaja agregacije trombocita. Manjak von Willebrandovog faktora (vWF), proteina potrebnog za normalno prianjanje trombocita na mjesto ozlijeđenog endotela, povezan je s višim stupnjem endometrioze dijagnosticiranim laparoskopski. Zaključak ovog preglednog rada je da trombociti mogu biti odgovorni za razvoj endometrioze odnosno da je poremećaj u agregaciji trombocita nađen u endometriotskim lezijama.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:105:461318
Study programmeTitle: Medicine (in English language)
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-10-08 08:14:41