Meibomian gland disease (MGD) is defined as chronic and disperse dysfunction of Meibomian glands. MGD is a disease that can be acquired or congenital. This disease is recognized as an obstruction of the terminal duct of the gland and changes in the composition of the tear film. MGD covers the part of Dry eye disease (DED) that is known as evaporative dry eye (EDE). EDE is connected to the lipid part of the tear film. The lipid part of the tear film plays an important role in stabilizing the tear film, without the lipid component the tear film evaporation time dramatically decreases. With the decrease of tear film stability some of the symptoms can start showing. The most common type of MGD is obstructive MGD. Obstructive MGD encompases a lot of subtypes but the most important one would have to be hyperkeratinization. Hyperkeratinization is important because the process of obstruction is directly connected to the histology and embryology of the glands. MDG has a specific parent of presentation, because of that there are a lot of methods that can be used to diagnose the disease. Although the methods used for diagnosis are precise and up to date there is a need to combine the different test to get the most accurate result. Finally the treatment for MDG is not complicated but some aspects of it can prove to be challenging for the patient whilst others may be painfull.