prikaz prve stranice dokumenta The risk of Lyme borreliosis infection following tick bite in Pristina region, Kosovo
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doctoral thesis
The risk of Lyme borreliosis infection following tick bite in Pristina region, Kosovo
Zagreb: University of Zagreb, School of Medicine, 2021. urn:nbn:hr:105:874026
Ponosheci-Biçaku, Albina
University of Zagreb
School of Medicine

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Ponosheci Biçaku, A. (2021). The risk of Lyme borreliosis infection following tick bite in Pristina region, Kosovo (Doctoral thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:874026

Ponosheci Biçaku, Albina. "The risk of Lyme borreliosis infection following tick bite in Pristina region, Kosovo." Doctoral thesis, University of Zagreb, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:105:874026

Ponosheci Biçaku, Albina. "The risk of Lyme borreliosis infection following tick bite in Pristina region, Kosovo." Doctoral thesis, University of Zagreb, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:105:874026

Ponosheci Biçaku, A. (2021). 'The risk of Lyme borreliosis infection following tick bite in Pristina region, Kosovo', Doctoral thesis, University of Zagreb, School of Medicine, accessed 04 May 2024, https://urn.nsk.hr/urn:nbn:hr:105:874026

Ponosheci Biçaku A. The risk of Lyme borreliosis infection following tick bite in Pristina region, Kosovo [Doctoral thesis]. Zagreb: University of Zagreb, School of Medicine; 2021 [cited 2024 May 04] Available at: https://urn.nsk.hr/urn:nbn:hr:105:874026

A. Ponosheci Biçaku, "The risk of Lyme borreliosis infection following tick bite in Pristina region, Kosovo", Doctoral thesis, University of Zagreb, School of Medicine, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:105:874026

Metadata
TitleThe risk of Lyme borreliosis infection following tick bite in Pristina region, Kosovo
Title (croatian)Rizik pojave Lajmske borelioze nakon ujeda krpelja u regiji Prištine, Kosovo
AuthorAlbina Ponosheci-Biçaku
MentorGoran Tešović (mentor)
Committee memberJosip Begovac (predsjednik povjerenstva)
Committee memberDalibor Vukelić (član povjerenstva)
Committee memberBranka Marinović (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
Zagreb
Defense date and country2021-07-05, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Public Health and Health Care
Epidemiology
Universal decimal classification
(UDC)		614 - Public health and hygiene. Accident prevention
Abstract
Aim: No clinical and seroprevalence studies for Lyme borreliosis (LB) in Kosovo have been publicly available thus far. Therefore, we performed a prospective observational study with the primary objective of defining the risk of developing Lyme borreliosis after a tick bite in Kosovo. Materials and methods: A total of 380 adult participants (≥18 years of age) with an embedded tick in the skin examined at the Clinic of Infectious Diseases, Pristina, were included in the study during the four years (January 2015-August 2018). Participants were followed by a six-month follow-up in order to detect the development of clinical manifestations of LB and/or seroconversion against Borrelia burgdorferi. Results: Most cases were seen in May and June in all study years. Erythema migrans (EM) was clinically diagnosed in 74/380 patients (19.5%, 95%CI 15.6-23.8). Only 15 clinically diagnosed EM (in seronegative patients) were serologically confirmed with seroconversion (2 months later). Three cases developed clinical manifestation with erythema migrans recidivans, multiple erythema, or several non-specific systemic symptoms. Doxycycline and amoxicillin were mainly used for the treatment of borrelial skin lesions. Conclusion: This assessment indicates the need for disease awareness and the importance of primary prevention measures, early diagnosis, and appropriate treatment.
Abstract (croatian)
Cilj istraživanja: Ne postoji nijedna objavljena studija o kliničkim osobitostima Lajmske bolesti na Kosovu, kao ni ona o seroprevalenciji. Ove činjenice potakle su nas na prospektivno istraživanje s glavnim ciljem utvrđivanja rizika nastanka lajmske borelioze nakon uboda krpelja na području Kosova. Materijali i metode: U studiju je ukupno uključeno 380 ispitanika starijih od 18 godina koji su se, s pričvršćenim krpeljom, javili na pregled u Odjel hitnog prijema Klinike za infektivne bolesti Sveučilišnog kliničkog centra Kosova u Prištini, tijekom četverogodišnjeg razdoblja (siječanj 2015. – kolovoz 2018). Ispitanici su praćeni šest mjeseci nakon uključivanja u studiju, s ciljem utvrđivanja rizika aktiviranja Lajmske borelioze na osnovu pojave klinički manifestne bolesti, odnosno pojave serokonverzije protiv Borrelia burgdorferi. Rezultati: Najveća aktivnost krpelja utvrđena je tijekom proljetnih mjeseci, svibnja i lipnja. U 74 ispitanika – 19,5% (95%CI 15,6-23,8) dijagnosticiran je solitarni erythema migrans (EM). Samo 15 klinički dijagnosticiranih EM (u seronegativnih bolesnika) serološki je potvrđeno serokonverzijom (2 mjeseca kasnije). U samo tri bolesnika razvile su se druge manifestacije infekcije borelijom – jedan je bolesnik imao recidivirajući formu EM, dok su druga dvojica imala ranu diseminiranu bolest. Bolesnici sa kožnom klinički manifestnom bolešću liječeni su sa doksiciklinom ili amoksicilinom. Zaključak: Ova analiza lokalne epidemiološke situacije ukazuje na potrebu podizanja svijesti o ovoj bolesti i važnosti mjera primarne prevencije, rane dijagnoze i odgovarajućeg liječenja.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:105:874026
Study programmeTitle: Biomedicine and Health Sciences
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti, područje biomedicine i zdravstvo (doktor/doktorica znanosti, područje biomedicine i zdravstvo)
Type of resourceText
Extent84 str.
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Public noteSumentor: Salih Ahmeti
Created on2021-10-25 11:37:24