prikaz prve stranice dokumenta The effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis
  Download
PDF 1.41 MB
doctoral thesis
The effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis
Zagreb: University of Zagreb, School of Medicine, 2021. urn:nbn:hr:105:042426
Kubat, Ozren
University of Zagreb
School of Medicine

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Kubat, O. (2021). The effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis (Doctoral thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:042426

Kubat, Ozren. "The effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis." Doctoral thesis, University of Zagreb, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:105:042426

Kubat, Ozren. "The effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis." Doctoral thesis, University of Zagreb, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:105:042426

Kubat, O. (2021). 'The effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis', Doctoral thesis, University of Zagreb, School of Medicine, accessed 10 November 2024, https://urn.nsk.hr/urn:nbn:hr:105:042426

Kubat O. The effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis [Doctoral thesis]. Zagreb: University of Zagreb, School of Medicine; 2021 [cited 2024 November 10] Available at: https://urn.nsk.hr/urn:nbn:hr:105:042426

O. Kubat, "The effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis", Doctoral thesis, University of Zagreb, School of Medicine, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:105:042426

Metadata
TitleThe effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis
Title (english)The effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis
AuthorOzren Kubat
MentorDomagoj Delimar (mentor)
Committee memberTomislav Smoljanović (predsjednik povjerenstva)
Committee memberBoris Brkljačić (član povjerenstva)
Committee memberTomislav Đapić (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
Zagreb
Defense date and country2021-07-08, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Orthopedics
Universal decimal classification
(UDC)		612 - Physiology
Abstract
Pre- and postoperative spinopelvic anatomy can influence results of distraction treatment in early onset scoliosis. I hypothesize patients with abnormal spinopelvic alignment have increased risk of proximal junctional kyphosis (PJK) during distraction treatment. Patients were treated between April 1997 and August 2014. A subsegment of patients were evaluated for quality of life. 135 patients were treated at an average age of 5.3 ± 2.83 years (range, 0.97-12.18), with minimum 2-year follow-up (average, 4.5 ± 2.6 years). 96 of 135 were included in the radiographic PJK study. 89 rib- and 46 spine-based distraction implants were used.Radiographic PJK developed in 38%, and clinical PJK in 18% of patients. Only pre-operative TK >50º increased risk for radiographic PJK (RR: 1.667, P=0.04). Pre-operative spinopelvic parameters did not increase risk for clinical PJK. Regarding quality of life, pelvic incidence –lumbar lordosis (PI-LL) mismatch > ±20o increased risk for poor outcomes through multiple domains while pelvic tilt (PT) >30°, implant type or fusion to pelvis had no effect. Preoperative TK >50º and spine-based distraction construct increased risk of radiographic PJK, and postoperative PI-LL >20º and PT ≥30º increased risk for clinical PJK. Preoperative PI >60° was shown to increase pain.
Abstract (croatian)
Pre- i postoperativna spinopelvina anatomija utječu na rezultate liječenja djece s ranopojavnom skoliozom. Hipoteza predmnijeva da bolesnici s abnormalnom spinopelvinom anatomijom imaju veći rizik od nastanka kifoze proksimalnog spoja (KPS) u tijeku liječenja rastućim instrumentacijama. Ova studija obuhvatila je bolesnike liječene od travnja 1997. do kolovoza 2014. Kod dijela bolesnika evaluirana je i kvaliteta života. 135 bolesnika liječeno je u prosječnoj dobi od 5,3 ± 2,83 godina (raspon, 0,97-12,18) s minimalnim praćenjem od 2 godine (prosjek, 4,5 ± 2,6 godina). 96 bolesnika uključeno je u ispitivanje radiografske kifoze. Ukupno je upotrijebljeno 89 kralježničnih i 46 rebrenih instrumentacija. Radiografska KPS pronađena je u 38% (36/96), dok je ona klinički značajna otkrivena u 18% (24/135) bolesnika. Preoperativna torakalna kifoza (TK) >50° povećala je rizik za radiografsku KPS (RR: 1.667, P=0.04), dok preoperativni spinopelvini parametri nisu utjecali na razvoj klinički značajne kifoze. Utjecaj navedenih anatomskih varijanti na kvalitetu života bio je slijedeći: razlika incidence zdjelice i lordoze (eng. pelvic incidence lumbar lordosis mismatch (PI-LL)) >20° uzrokuje loš rezultat u multiplim domenama, nagib zdjelice (eng. pelvic tilt (PT)) >30°. Preoperativna TK >50° i kralježnične instrumentacije povećavaju rizik pojave radiografske kifoze, a postoperativni PI-LL >20° i PT ≥30º povećavaju rizik od klinički značajne kifoze. Preoperativna PI >60° uzrokuje bolove.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:105:042426
Study programmeTitle: Biomedicine and Health Sciences
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti, područje biomedicine i zdravstvo (doktor/doktorica znanosti, područje biomedicine i zdravstvo)
Type of resourceText
Extent81 str.
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Public noteSumentor: Ron El-Hawary
Created on2021-11-02 08:18:27