prikaz prve stranice dokumenta Age-Specific Excretion of Calcium, Oxalate, Citrate, and Glycosaminoglycans and Their Ratios in Healthy Children and Children with Urolithiasis
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Scientific paper - Original scientific paper
Age-Specific Excretion of Calcium, Oxalate, Citrate, and Glycosaminoglycans and Their Ratios in Healthy Children and Children with Urolithiasis
Biomolecules, 11 (2021), 5; 758. https://doi.org/10.3390/biom11050758
Turudić, Daniel; Golubić, Anja Tea; Lovrić, Mila; Bilić, Marko; Milošević, Danko

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Turudić, D., Golubić, A. T., Lovrić, M., Bilić, M. & Milošević, D. (2021). Age-Specific Excretion of Calcium, Oxalate, Citrate, and Glycosaminoglycans and Their Ratios in Healthy Children and Children with Urolithiasis. Biomolecules, 11. (5). doi: 10.3390/biom11050758

Turudić, Daniel, et al. "Age-Specific Excretion of Calcium, Oxalate, Citrate, and Glycosaminoglycans and Their Ratios in Healthy Children and Children with Urolithiasis." Biomolecules, vol. 11, no. 5, 2021. https://doi.org/10.3390/biom11050758

Turudić, Daniel, Anja Tea Golubić, Mila Lovrić, Marko Bilić and Danko Milošević. "Age-Specific Excretion of Calcium, Oxalate, Citrate, and Glycosaminoglycans and Their Ratios in Healthy Children and Children with Urolithiasis." Biomolecules 11, no. 5 (2021). https://doi.org/10.3390/biom11050758

Turudić, D., et al. (2021) 'Age-Specific Excretion of Calcium, Oxalate, Citrate, and Glycosaminoglycans and Their Ratios in Healthy Children and Children with Urolithiasis', Biomolecules, 11(5). doi: 10.3390/biom11050758

Turudić D, Golubić AT, Lovrić M, Bilić M, Milošević D. Age-Specific Excretion of Calcium, Oxalate, Citrate, and Glycosaminoglycans and Their Ratios in Healthy Children and Children with Urolithiasis. Biomolecules [Internet]. 2021 May 19 [cited 2024 November 26];11(5). doi: 10.3390/biom11050758

D. Turudić, A. T. Golubić, M. Lovrić, M. Bilić and D. Milošević, "Age-Specific Excretion of Calcium, Oxalate, Citrate, and Glycosaminoglycans and Their Ratios in Healthy Children and Children with Urolithiasis", Biomolecules, vol. 11, no. 5, May 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:952814. [Accessed: 26 November 2024]

Metadata
Title (english)Age-Specific Excretion of Calcium, Oxalate, Citrate, and Glycosaminoglycans and Their Ratios in Healthy Children and Children with Urolithiasis
AuthorDaniel Turudić
AuthorAnja Tea Golubić
AuthorMila Lovrić
AuthorMarko Bilić
AuthorDanko Milošević
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Nuclear Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Nuclear Medicine
Abstract (english)
We analyzed children with urolithiasis with age- and gender-matched healthy children. Calcium (mmol/mmol creatinine) and the calcium/citrate ratio (mol/mmol) are the only variables that differentiate children before puberty from healthy children (ROC analysis confirmed only calcium/citrate as a significant variable with cut-off value > 0.84). Peri-pubertal children are distinguished from age- and gender-matched healthy children by the following variables: citrate (mmol/mol creatinine), calcium/citrate (mol/mmol), oxalate/glycosaminoglycans (mmol/g), oxalate/citrate ratios (mmol/mmol) and oxalate/(citrate × glycosaminoglycans) (mol oxalate × mol creatinine)/(mol citrate × g glycosaminoglycans). All variables were confirmed by ROC analysis with cut-off values ≤ 327.87, >1.02, >11.24, >0.12 and >0.03, respectively. These results indicate a different risk of urinary stones development before puberty vs. pubertal/postpubertal children and increasing importance (deficiency) of citrate and glycosaminoglycans in such children. J48 classifier confirmed the importance of the oxalate/(citrate × glycosaminoglycans) and the calcium/citrate ratios (Ox/Cit × GAG 0.22 and Cit/GAG 0.612) with the practically applicable classification tree for distinguishing between pubertal/postpubertal children with urolithiasis with age- and gender-matched healthy children.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleBiomolecules
Numberingvol. 11, no. 5, 758
e-ISSN2218-273X
DOIhttps://doi.org/10.3390/biom11050758
URN:NBNurn:nbn:hr:105:952814
Publication2021-05-19
Document URLhttps://www.mdpi.com/2218-273X/11/5/758
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2021-11-03 12:09:39