prikaz prve stranice dokumenta The influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds
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master's thesis
The influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds
Zagreb: University of Zagreb, School of Medicine, 2021. urn:nbn:hr:105:338196
Wahl, Viviana
University of Zagreb
School of Medicine
Department of Surgery

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Wahl, V. (2021). The influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:338196

Wahl, Viviana. "The influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds." Master's thesis, University of Zagreb, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:105:338196

Wahl, Viviana. "The influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds." Master's thesis, University of Zagreb, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:105:338196

Wahl, V. (2021). 'The influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds', Master's thesis, University of Zagreb, School of Medicine, accessed 14 January 2025, https://urn.nsk.hr/urn:nbn:hr:105:338196

Wahl V. The influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2021 [cited 2025 January 14] Available at: https://urn.nsk.hr/urn:nbn:hr:105:338196

V. Wahl, "The influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:105:338196

Metadata
TitleThe influence of vacuum assisted closure therapy on bacterial growth and biofilm development in the wounds
Title (croatian)Utjecaj terapije za zatvaranje rana vakuumom na rast bakterija i nastanak biofilma u ranama
AuthorViviana Wahl
MentorKrešimir Bulić (mentor)
Committee memberDavor Mijatović (predsjednik povjerenstva)
Committee memberKrešimir Bulić (član povjerenstva)
Committee memberTomislav Meštrović (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Surgery)
Zagreb
Defense date and country2021-07-16, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Abstract
Vacuum assisted closure therapy was developed for the needs of plastic surgery in the 90s. Primarily used for the treatment of patients with large chronic wounds, the usage nowadays extends to area of medicine and veterinary, for all types of large, chronic and infected wounds, where increased drainage of the exudate and help with wound closure is needed. Vacuum assisted closure therapy uses sub-atmospheric pressure between 50 and 200 mmHg which facilitates drainage of fluids, reduces swelling, mechanically removes bacteria and increases blood flow. Precaution is needed with poorly debrided wounds, with irradiated tissue, with fragile blood vessels and with patients on anticoagulation therapy. The foam with 400 to 600 micrometer pores, covers the wound area completely, over which protective seal is placed. Tubing connects the seal with the vacuum pump, on which continuous, variable or intermittent mode of action and level of negative pressure are set. Since the early nineties numerous research articles were written on the topic of negative pressure and vacuum therapy and they mostly agree, that utilisation of negative pressure improves rate of granulation tissue formation, decreases time of healing and assists with infectious process in the wound. In-vitro and in-vivo research shows good clinical results. Additionally, gene testing and microbiological results are encouraging.
Abstract (croatian)
Terapija kroničnih rana uz pomoć vakuuma razvijena je za potrebe plastične kirurgije u početku 90-ih godina. Primarno korišten za liječenje bolesnika s velikim kroničnim ranama, danas se koristi na području medicine i veterine, za sve vrste velikih, kroničnih i zaraženih rana, gdje je potrebna povećana drenaža eksudata i pomoć pri zatvaranju rana. Terapija negativnim tlakom koristi subatmosferski tlak između 50 i 200 mmHg što olakšava drenažu tekućina, smanjuje oticanje, mehanički uklanja bakterije i povećava protok krvi. Potreban je oprez sa loše očišćenim ranama, s ozračenim tkivom, krhkim krvnim žilama i s pacijentima na antikoagulacijskoj terapiji. Pjena s porama od 400 do 600 mikrometara u potpunosti pokriva područje rane preko koje se postavlja zaštitna folija. Cijev spaja zaštitnu foliju s vakuumskom pumpom, na kojoj se kontroliraju kontinuirani, promjenjivi ili isprekidani način djelovanja i razina negativnog tlaka. Od početka devedesetih na temu negativnog tlaka i vakuumske terapije napisani su brojni istraživački članci, koji se uglavnom slažu da korištenje negativnog tlaka poboljšava brzinu stvaranja granulacijskog tkiva, smanjuje vrijeme zacjeljivanja i pomaže kod zaraznog procesa u rani. In-vitro i in-vivo istraživanja pokazuju dobre kliničke rezultate. Također ohrabruju rezultati genetskog ispitivanja i mikrobiološki rezultati.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:105:338196
Study programmeTitle: Medicine (in English language)
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2021-12-22 10:52:24