prikaz prve stranice dokumenta Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection
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Scientific paper - Original scientific paper
Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection
Viruses, 13 (2021), 9; 1728. https://doi.org/10.3390/v13091728
Ljubin-Sternak, Sunčanica; Slović, Anamarija; Mijač, Maja; Jurković, Mirna; Forčić, Dubravko; Ivković-Jureković, Irena; Tot, Tatjana; Vraneš, Jasmina

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Ljubin Sternak, S., Slović, A., Mijač, M., Jurković, M., Forčić, D., Ivković Jureković, I. ... Vraneš, J. (2021). Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection. Viruses, 13. (9). doi: 10.3390/v13091728

Ljubin Sternak, Sunčanica, et al. "Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection." Viruses, vol. 13, no. 9, 2021. https://doi.org/10.3390/v13091728

Ljubin Sternak, Sunčanica, Anamarija Slović, Maja Mijač, Mirna Jurković, Dubravko Forčić, Irena Ivković Jureković, Tatjana Tot and Jasmina Vraneš. "Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection." Viruses 13, no. 9 (2021). https://doi.org/10.3390/v13091728

Ljubin Sternak, S., et al. (2021) 'Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection', Viruses, 13(9). doi: 10.3390/v13091728

Ljubin Sternak S, Slović A, Mijač M, Jurković M, Forčić D, Ivković Jureković I, and sur.. Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection. Viruses [Internet]. 2021 August 31 [cited 2025 January 21];13(9). doi: 10.3390/v13091728

S. Ljubin Sternak, et al., "Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection", Viruses, vol. 13, no. 9, August 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:756774. [Accessed: 21 January 2025]

Metadata
Title (english)Prevalence and Molecular Characterization of Human Bocavirus Detected in Croatian Children with Respiratory Infection
AuthorSunčanica Ljubin-Sternak
AuthorAnamarija Slović
AuthorMaja Mijač
AuthorMirna Jurković
AuthorDubravko Forčić
AuthorIrena Ivković-Jureković
AuthorTatjana Tot
AuthorJasmina Vraneš
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Medical Microbiology and Parasitology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Abstract (english)
Human bocavirus (HBoV) 1 is considered an important respiratory pathogen, while the role of HBoV2-4 in clinical disease remains somewhat controversial. Since, they are characterized by a rapid evolution, worldwide surveillance of HBoVs’ genetics is necessary. This study explored the prevalence of HBoV genotypes in pediatric patients with respiratory tract infection in Croatia and studied their phylogeny. Using multiplex PCR for 15 respiratory viruses, we investigated 957 respiratory samples of children up to 18 years of age with respiratory tract infection obtained from May 2017 to March 2021 at two different hospitals in Croatia. Amplification of HBoV near-complete genome or three overlapping fragments was performed, sequenced, and their phylogenetic inferences constructed. HBoV was detected in 7.6% children with a median age of 1.36 years. Co-infection was observed in 82.2% samples. Sequencing was successfully performed on 29 HBoV positive samples, and all belonged to HBoV1. Croatian HBoV1 sequences are closely related to strains isolated worldwide, and no phylogenetic grouping based on mono- or co-infection cases or year of isolation was observed. Calculated rates of evolution for HBoV1 were 10−4 and 10−5 substitutions per site and year. Recombination was not detected among sequences from this study.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleViruses
Numberingvol. 13, no. 9, 1728
e-ISSN1999-4915
DOIhttps://doi.org/10.3390/v13091728
URN:NBNurn:nbn:hr:105:756774
Publication2021-08-31
Document URLhttps://www.mdpi.com/1999-4915/13/9/1728
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-04-07 11:45:10