prikaz prve stranice dokumenta Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157
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Scientific paper - Original scientific paper
Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157
Biology, 10 (2021), 9; 891. https://doi.org/10.3390/biology10090891
Tlak Gajger, Ivana; Smodiš Škerl, Maja Ivana; Šoštarić, Petra; Šuran, Jelena; Sikirić, Predrag; Vlainić, Josipa

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Tlak Gajger, I., Smodiš Škerl, M. I., Šoštarić, P., Šuran, J., Sikirić, P. & Vlainić, J. (2021). Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157. Biology, 10. (9). doi: 10.3390/biology10090891

Tlak Gajger, Ivana, et al. "Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157." Biology, vol. 10, no. 9, 2021. https://doi.org/10.3390/biology10090891

Tlak Gajger, Ivana, Maja Ivana Smodiš Škerl, Petra Šoštarić, Jelena Šuran, Predrag Sikirić and Josipa Vlainić. "Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157." Biology 10, no. 9 (2021). https://doi.org/10.3390/biology10090891

Tlak Gajger, I., et al. (2021) 'Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157', Biology, 10(9). doi: 10.3390/biology10090891

Tlak Gajger I, Smodiš Škerl MI, Šoštarić P, Šuran J, Sikirić P, Vlainić J. Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157. Biology [Internet]. 2021 September 09 [cited 2024 April 28];10(9). doi: 10.3390/biology10090891

I. Tlak Gajger, M. I. Smodiš Škerl, P. Šoštarić, J. Šuran, P. Sikirić and J. Vlainić, "Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157", Biology, vol. 10, no. 9, September 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:973445. [Accessed: 28 April 2024]

Metadata
Title (english)Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157
AuthorIvana Tlak Gajger
AuthorMaja Ivana Smodiš Škerl
AuthorPetra Šoštarić
AuthorJelena Šuran
AuthorPredrag Sikirić
AuthorJosipa Vlainić
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Pharmacology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Abstract (english)
Various factors contribute to a decline in diversity and number of bees. Here, an integrated approach in experimental BPC 157 therapy was implemented, combining laboratory-controlled and field study results. The aim of a study was to assess the effects of BPC 157 additional feeding of newly emerged worker honeybees on few biochemical and immunological parameters in hemolymph (glucose, trehalose, lipids, proteins, vitellogenin, glucose-oxidase (GOX)), and hypopharyngeal gland (HPG), in laboratory-controlled conditions. Additionally, to examine the physiological status of protein digestion, the enzymatic activity of leucine aminopeptidase (LAP) in the mid-guts of worker honeybees was analyzed. It was found that individual honeybees, in hoarding cages, following BPC 157 administration through carbohydrate food, showed positive physiological changes when compared to the control groups. Those results were complemented by strong and visible LAP activity, particularly noticeable in the apical parts of the epithelial cells in the mid-guts of young worker honeybees originated from treated hives, suggesting a link between alternative oral therapy with BPC 157 and honeybees’ immunity.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleBiology
Numberingvol. 10, no. 9, 891
e-ISSN2079-7737
DOIhttps://doi.org/10.3390/biology10090891
URN:NBNurn:nbn:hr:105:973445
Publication2021-09-09
Document URLhttps://www.mdpi.com/2079-7737/10/9/891
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-04-26 09:18:53