prikaz prve stranice dokumenta Comparison of systemic inflammatory responses of proximal femoral nail versus dynamic hip screw after treatment of patients with pertrochanteric fractures: A prospective comparative study
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Scientific paper - Original scientific paper
Comparison of systemic inflammatory responses of proximal femoral nail versus dynamic hip screw after treatment of patients with pertrochanteric fractures: A prospective comparative study
Acta Orthopaedica et Traumatologica Turcica, 55 (2021), 4; 293-298. https://doi.org/10.5152/j.aott.2021.20193
Grezda, Kushtrim; Jelić, Mislav; Daci, Armond; Bytyqi, Cen; Kida, Qerim

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Grezda, K., Jelić, M., Daci, A., Bytyqi, C. & Kida, Q. (2021). Comparison of systemic inflammatory responses of proximal femoral nail versus dynamic hip screw after treatment of patients with pertrochanteric fractures: A prospective comparative study. Acta Orthopaedica et Traumatologica Turcica, 55. (4), 293-298. doi: 10.5152/j.aott.2021.20193

Grezda, Kushtrim, et al. "Comparison of systemic inflammatory responses of proximal femoral nail versus dynamic hip screw after treatment of patients with pertrochanteric fractures: A prospective comparative study." Acta Orthopaedica et Traumatologica Turcica, vol. 55, no. 4, 2021, pp. 293-298. https://doi.org/10.5152/j.aott.2021.20193

Grezda, Kushtrim, Mislav Jelić, Armond Daci, Cen Bytyqi and Qerim Kida. "Comparison of systemic inflammatory responses of proximal femoral nail versus dynamic hip screw after treatment of patients with pertrochanteric fractures: A prospective comparative study." Acta Orthopaedica et Traumatologica Turcica 55, no. 4 (2021): 293-298. https://doi.org/10.5152/j.aott.2021.20193

Grezda, K., et al. (2021) 'Comparison of systemic inflammatory responses of proximal femoral nail versus dynamic hip screw after treatment of patients with pertrochanteric fractures: A prospective comparative study', Acta Orthopaedica et Traumatologica Turcica, 55(4), pp. 293-298. doi: 10.5152/j.aott.2021.20193

Grezda K, Jelić M, Daci A, Bytyqi C, Kida Q. Comparison of systemic inflammatory responses of proximal femoral nail versus dynamic hip screw after treatment of patients with pertrochanteric fractures: A prospective comparative study. Acta Orthopaedica et Traumatologica Turcica [Internet]. 2021 August [cited 2024 May 11];55(4):293-298. doi: 10.5152/j.aott.2021.20193

K. Grezda, M. Jelić, A. Daci, C. Bytyqi and Q. Kida, "Comparison of systemic inflammatory responses of proximal femoral nail versus dynamic hip screw after treatment of patients with pertrochanteric fractures: A prospective comparative study", Acta Orthopaedica et Traumatologica Turcica, vol. 55, no. 4, pp. 293-298, August 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:274943. [Accessed: 11 May 2024]

Metadata
Title (english)Comparison of systemic inflammatory responses of proximal femoral nail versus dynamic hip screw after treatment of patients with pertrochanteric fractures: A prospective comparative study
AuthorKushtrim Grezda
AuthorMislav Jelić
AuthorArmond Daci
AuthorCen Bytyqi
AuthorQerim Kida
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Orthopedics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Orthopedics
Abstract (english)
Objective: The aim of this study was to investigate the differences between the induction of early postoperative inflammatory response and muscle tissue injury biomarkers after treatment of pertrochanteric fractures by dynamic hip screw (DHS) or proximal femoral nail (PFN). Methods: In this prospective comparative study, 40 patients with AO-Müller/Orthopaedic Trauma Association (AO/OTA) 31. A1-31.A2 pertrochanteric fractures were enrolled and allocated one of the two groups based on the treatment type: group DHS, (n =20,mean age = 78.4 ± 6.9 years) and group PFN (n = 20, mean age = 77.75 ± 7.0 years). Operation time was recorded in both groups. In each patient, circulating levels of high sensitivity interleukin-6 (hs-IL-6), C-reactive protein (CRP), and creatine kinase (CK), and erythrocyte sedimentation rate (ESR)weremeasured fromblood samples collected 1 hour preoperatively and 24 hours postoperatively. Results: The operation time was slightly shorter in group PFN than in group DHS (51.9 ± 21.1 and 38 ± 15.2 min, respectively; P = 0.02). DHS and PFN both increased hs-IL-6 (143.81 ± 89.12 and 94.13 ± 67.14, respectively), CRP (98.84 ± 31.81 and 104.4 ± 31.80, respectively), and CK (400.8 ± 31.81 and 250.7 ± 31.80, respectively) 24 hours postoperatively. However, PFN compared to DHS resulted in a lesser increase from baseline to 24 hours postoperatively only in hs IL-6 (58.91 ± 59.02 vs 113.30 ± 76.24, respectively; P = 0.0016) and CK (163.6 ± 123.3 vs 310.0 ± 198.3, respectively; P < 0.0001).Moreover, there was a positive correlation of CK levels' surgery time in DHS (r = 0.38, P = 0.0065) and PFN (r = 0.45, P = 0.0013). Conclusion: The results of this study have shown that PFN can induce a lower early postoperative inflammatory response and muscle tissue injury based on the assessment of hs-IL-6 and CK levels, compared to DHS in after the treatment patients pertrochanteric fractures.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleActa Orthopaedica et Traumatologica Turcica
Numberingvol. 55, no. 4, pp. 293-298
p-ISSN1017-995X
e-ISSN2589-1294
DOIhttps://doi.org/10.5152/j.aott.2021.20193
URN:NBNurn:nbn:hr:105:274943
Publication2021-08
Document URLhttps://www.aott.org.tr/en/comparison-of-systemic-inflammatory-responses-of-proximal-femoral-nail-versus-dynamic-hip-screw-after-treatment-of-patients-with-pertrochanteric-fractures-a-prospective-comparative-study-137163
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2022-05-09 11:04:26