prikaz prve stranice dokumenta Epidemiological characteristics, baseline clinical features, and outcomes of critically ill patients treated in a coronavirus disease 2019 tertiary center in continental Croatia
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Scientific paper - Original scientific paper
Epidemiological characteristics, baseline clinical features, and outcomes of critically ill patients treated in a coronavirus disease 2019 tertiary center in continental Croatia
Croatian Medical Journal, 63 (2022), 1; 6-15. https://doi.org/10.3325/cmj.2022.63.6
Čučković, Marcela; Drmić, Željka; Pražetina, Marko; Tipura, Danijela; Ćurčić, Maja; Miko, Ivan; Mihelčić, Antonija; Romić, Andrea; Kukoč, Andrea; Blagaj, Vanja; Lasić, Hrvoje; Dolenc, Emil; Hleb, Sonja; Almahariq, Hani; Šribar, Andrej; Peršec, Jasminka; Lukšić, Ivica More authors...

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Čučković, M., Drmić, Ž., Pražetina, M., Tipura, D., Ćurčić, M., Miko, I. ... Lukšić, I. (2022). Epidemiological characteristics, baseline clinical features, and outcomes of critically ill patients treated in a coronavirus disease 2019 tertiary center in continental Croatia. Croatian Medical Journal, 63. (1), 6-15. doi: 10.3325/cmj.2022.63.6

Čučković, Marcela, et al. "Epidemiological characteristics, baseline clinical features, and outcomes of critically ill patients treated in a coronavirus disease 2019 tertiary center in continental Croatia." Croatian Medical Journal, vol. 63, no. 1, 2022, pp. 6-15. https://doi.org/10.3325/cmj.2022.63.6

Čučković, Marcela, Željka Drmić, Marko Pražetina, Danijela Tipura, Maja Ćurčić, Ivan Miko, Antonija Mihelčić, et al. "Epidemiological characteristics, baseline clinical features, and outcomes of critically ill patients treated in a coronavirus disease 2019 tertiary center in continental Croatia." Croatian Medical Journal 63, no. 1 (2022): 6-15. https://doi.org/10.3325/cmj.2022.63.6

Čučković, M., et al. (2022) 'Epidemiological characteristics, baseline clinical features, and outcomes of critically ill patients treated in a coronavirus disease 2019 tertiary center in continental Croatia', Croatian Medical Journal, 63(1), pp. 6-15. doi: 10.3325/cmj.2022.63.6

Čučković M, Drmić Ž, Pražetina M, Tipura D, Ćurčić M, Miko I, and sur.. Epidemiological characteristics, baseline clinical features, and outcomes of critically ill patients treated in a coronavirus disease 2019 tertiary center in continental Croatia. Croatian Medical Journal [Internet]. 2022 February 28 [cited 2024 November 23];63(1):6-15. doi: 10.3325/cmj.2022.63.6

M. Čučković, et al., "Epidemiological characteristics, baseline clinical features, and outcomes of critically ill patients treated in a coronavirus disease 2019 tertiary center in continental Croatia", Croatian Medical Journal, vol. 63, no. 1, pp. 6-15, February 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:607781. [Accessed: 23 November 2024]

Metadata
Title (english)Epidemiological characteristics, baseline clinical features, and outcomes of critically ill patients treated in a coronavirus disease 2019 tertiary center in continental Croatia
AuthorMarcela Čučković
AuthorŽeljka Drmić
AuthorMarko Pražetina
AuthorDanijela Tipura
AuthorMaja Ćurčić
AuthorIvan Miko
AuthorAntonija Mihelčić
AuthorAndrea Romić
AuthorAndrea Kukoč
AuthorVanja Blagaj
AuthorHrvoje Lasić
AuthorEmil Dolenc
AuthorSonja Hleb
AuthorHani Almahariq
AuthorAndrej Šribar
AuthorJasminka Peršec
AuthorIvica Lukšić
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Maxillofacial Surgery and Dentistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Abstract (english)
Aim: To describe epidemiological characteristics and baseline clinical features, laboratory findings at intensive care unit (ICU) admission, and survival rates of critically ill coronavirus disease 2019 (COVID-19) patients treated at a tertiary institution specialized for COVID-19 patients. ----- Methods: This retrospective study recruited 692 patients (67.1% men). Baseline demographic data, major comorbidities, anthropometric measurements, clinical features, and laboratory findings at admission were compared between survivors and non-survivors. ----- Results: The median age was 72 (64-78) years. The median body mass index was 29.1 kg/m2. The most relevant comorbidities were diabetes mellitus (32.6%), arterial hypertension (71.2%), congestive heart failure (19.1%), chronic kidney disease (12.6%), and hematological disorders (10.3%). The median number of comorbidities was 3 and median Charlson Comorbidity Index (CCI) was 5. A total of 61.8% patients received high-flow nasal oxygen therapy (HFNO) and 80.5% received mechanical ventilation (MV). Median duration of HFNO was 3, and that of MV was 7 days. ICU mortality rate was 72.7%. Survivors had significantly lower age, number of comorbidities, CCI, sequential organ failure assessment score, serum ferritin, C-reactive protein, D-dimer, and procalcitonin, interleukin-6, lactate, white blood cell, and neutrophil counts. They also had higher lymphocyte counts, PaO2/FiO2 ratio, and glomerular filtration rate at admission. Length of ICU stay was 9 days. The median survival was 11 days for mechanically ventilated patients, and 24 days for patients who were not mechanically ventilated. ----- Conclusion: The parameters that differentiate survivors from non-survivors are in agreement with published data. Further multivariate analyses are warranted to identify individual mortality risk factors.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian Medical Journal
Numberingvol. 63, no. 1, pp. 6-15
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2022.63.6
URN:NBNurn:nbn:hr:105:607781
Publication2022-02-28
Document URLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895330/
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2022-05-19 11:35:56