prikaz prve stranice dokumenta The onset of ulcerative colitis upon Helicobacter pylori eradication in a 72-year-old woman: report of a rare case with a 3-year follow-up
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Scientific paper - Case study
The onset of ulcerative colitis upon Helicobacter pylori eradication in a 72-year-old woman: report of a rare case with a 3-year follow-up
BMC Gastroenterology, 21 (2021), 1; 303. https://doi.org/10.1186/s12876-021-01876-5
Homolak, Jan; Nikolić, Marko; Potoč, D.; Živković, M.; Bakula, D.; Budimir, Ivan; Pavić, I.; Hrabar, Davor; Ljubičić, Neven; Vražić, D.

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Homolak, J., Nikolić, M., Potoč, D., Živković, M., Bakula, D., Budimir, I. ... Vražić, D. (2021). The onset of ulcerative colitis upon Helicobacter pylori eradication in a 72-year-old woman: report of a rare case with a 3-year follow-up. BMC Gastroenterology, 21. (1). doi: 10.1186/s12876-021-01876-5

Homolak, Jan, et al. "The onset of ulcerative colitis upon Helicobacter pylori eradication in a 72-year-old woman: report of a rare case with a 3-year follow-up." BMC Gastroenterology, vol. 21, no. 1, 2021. https://doi.org/10.1186/s12876-021-01876-5

Homolak, Jan, Marko Nikolić, D. Potoč, M. Živković, D. Bakula, Ivan Budimir, I. Pavić, Davor Hrabar, Neven Ljubičić and D. Vražić. "The onset of ulcerative colitis upon Helicobacter pylori eradication in a 72-year-old woman: report of a rare case with a 3-year follow-up." BMC Gastroenterology 21, no. 1 (2021). https://doi.org/10.1186/s12876-021-01876-5

Homolak, J., et al. (2021) 'The onset of ulcerative colitis upon Helicobacter pylori eradication in a 72-year-old woman: report of a rare case with a 3-year follow-up', BMC Gastroenterology, 21(1). doi: 10.1186/s12876-021-01876-5

Homolak J, Nikolić M, Potoč D, Živković M, Bakula D, Budimir I, and sur.. The onset of ulcerative colitis upon Helicobacter pylori eradication in a 72-year-old woman: report of a rare case with a 3-year follow-up. BMC Gastroenterology [Internet]. 2021 July 31 [cited 2024 December 27];21(1). doi: 10.1186/s12876-021-01876-5

J. Homolak, et al., "The onset of ulcerative colitis upon Helicobacter pylori eradication in a 72-year-old woman: report of a rare case with a 3-year follow-up", BMC Gastroenterology, vol. 21, no. 1, July 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:604206. [Accessed: 27 December 2024]

Metadata
Title (english)The onset of ulcerative colitis upon Helicobacter pylori eradication in a 72-year-old woman: report of a rare case with a 3-year follow-up
AuthorJan Homolak
AuthorMarko Nikolić
AuthorD. Potoč
AuthorM. Živković
AuthorD. Bakula
AuthorIvan Budimir
AuthorI. Pavić
AuthorDavor Hrabar
AuthorNeven Ljubičić
AuthorD. Vražić
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Pharmacology)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Abstract (english)
Background: Epidemiological studies suggest an inverse association between H. pylori infection/exposure and inflammatory bowel disease prevalence/incidence, however, there are no reports of individual patients who developed a "non-transient" ulcerative colitis (UC) following H. pylori eradication. ----- Case presentation: We report a case of a 72-year-old female with an elderly-onset UC developed upon H. pylori eradication and a 3-year follow-up of the progression to steroid-dependent colitis complicated with enteropathic arthritis and final containment of the disease with golimumab. In our patient, H. pylori eradication was associated with the development of pancolitis that evolved into clinically, endoscopically, and pathohistologically confirmed UC. ----- Conclusions: The case of our patient provides a unique clinical context for a growing body of literature suggesting molecular mechanisms involved in the interaction of genes, environment, and microbiota to be of critical importance in the etiopathogenesis of UC, and thus, provides a valuable set of complementary translational information for preclinical and epidemiological research on the topic.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleBMC Gastroenterology
Numberingvol. 21, no. 1, 303
e-ISSN1471-230X
DOIhttps://doi.org/10.1186/s12876-021-01876-5
URN:NBNurn:nbn:hr:105:604206
Publication2021-07-31
Document URLhttps://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-021-01876-5
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-06-02 07:32:54