prikaz prve stranice dokumenta Extracorporeal blood purification is associated with improvement in biochemical and clinical variables in the critically-ill COVID-19 patients
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Scientific paper - Original scientific paper
Extracorporeal blood purification is associated with improvement in biochemical and clinical variables in the critically-ill COVID-19 patients
Therapeutic Apheresis and Dialysis, 26 (2022), 2; 316-329. https://doi.org/10.1111/1744-9987.13730
Premužić, Vedran; Babel, Jakša; Gardijan, Danilo; Lapić, Ivana; Gabelica, Rajka; Ostojić, Zvonimir; Lozić, Marin; Pavliša, Gordana; Hrabak, Maja; Knežević, Josip; Rogić, Dunja; Mihaljević, Slobodan

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Premužić, V., Babel, J., Gardijan, D., Lapić, I., Gabelica, R., Ostojić, Z. ... Mihaljević, S. (2022). Extracorporeal blood purification is associated with improvement in biochemical and clinical variables in the critically-ill COVID-19 patients. Therapeutic Apheresis and Dialysis, 26. (2), 316-329. doi: 10.1111/1744-9987.13730

Premužić, Vedran, et al. "Extracorporeal blood purification is associated with improvement in biochemical and clinical variables in the critically-ill COVID-19 patients." Therapeutic Apheresis and Dialysis, vol. 26, no. 2, 2022, pp. 316-329. https://doi.org/10.1111/1744-9987.13730

Premužić, Vedran, Jakša Babel, Danilo Gardijan, Ivana Lapić, Rajka Gabelica, Zvonimir Ostojić, Marin Lozić, et al. "Extracorporeal blood purification is associated with improvement in biochemical and clinical variables in the critically-ill COVID-19 patients." Therapeutic Apheresis and Dialysis 26, no. 2 (2022): 316-329. https://doi.org/10.1111/1744-9987.13730

Premužić, V., et al. (2022) 'Extracorporeal blood purification is associated with improvement in biochemical and clinical variables in the critically-ill COVID-19 patients', Therapeutic Apheresis and Dialysis, 26(2), pp. 316-329. doi: 10.1111/1744-9987.13730

Premužić V, Babel J, Gardijan D, Lapić I, Gabelica R, Ostojić Z, and sur.. Extracorporeal blood purification is associated with improvement in biochemical and clinical variables in the critically-ill COVID-19 patients. Therapeutic Apheresis and Dialysis [Internet]. 2022 April [cited 2024 November 09];26(2):316-329. doi: 10.1111/1744-9987.13730

V. Premužić, et al., "Extracorporeal blood purification is associated with improvement in biochemical and clinical variables in the critically-ill COVID-19 patients", Therapeutic Apheresis and Dialysis, vol. 26, no. 2, pp. 316-329, April 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:457439. [Accessed: 09 November 2024]

Metadata
Title (english)Extracorporeal blood purification is associated with improvement in biochemical and clinical variables in the critically-ill COVID-19 patients
AuthorVedran Premužić
AuthorJakša Babel
AuthorDanilo Gardijan
AuthorIvana Lapić
AuthorRajka Gabelica
AuthorZvonimir Ostojić
AuthorMarin Lozić
AuthorGordana Pavliša
AuthorMaja Hrabak
AuthorJosip Knežević
AuthorDunja Rogić
AuthorSlobodan Mihaljević
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Anaesthesiology, Resuscitation and Intensive Care in Surgical Specialities)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Anesthesiology and Reanimatology
Abstract (english)
This study tried to investigate the impact of oXiris filter on both clinical and laboratory parameters in critically-ill COVID-19 intensive care unit (ICU) patients receiving extracorporeal blood purification and the clinical setting for the initiation of therapy. A consecutive sample of 15 ICU patients with COVID-19 was treated with oXiris membrane for blood purification or for support of renal function due to acute kidney injury. We have included 19 non treated ICU COVID-19 patients as a control group. Two chest x-rays were analyzed for determining the chest x-ray severity score. We have found a significant decrease of SOFA score, respiratory status improved and the chest x-ray severity score was significantly decreased after 72 h of treatment. IL-6 significantly decreased after 72 h of treatment while other inflammatory markers did not. Respiratory status in the control group worsened as well as increase in SOFA score and chest x-ray severity score. Survived patients have shorter time from the onset of symptoms before starting with extracorporeal blood purification treatment and shorter time on vasoactive therapy and invasive respiratory support than deceased patients. Critically-ill patients with COVID-19 treated with extracorporeal blood purification survived significantly longer than other ICU COVID-19 patients. Treatment with oXiris membrane provides significant reduction of IL-6, leads to improvement in respiratory status, chest x-ray severity score, and reduction of SOFA score severity. Our results can suggest that ICU COVID-19 patients in an early course of a disease could be potentially a target group for earlier initiation of extracorporeal blood purification.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleTherapeutic Apheresis and Dialysis
Numberingvol. 26, no. 2, pp. 316-329
p-ISSN1744-9979
e-ISSN1744-9987
DOIhttps://doi.org/10.1111/1744-9987.13730
URN:NBNurn:nbn:hr:105:457439
Publication2022-04
Document URLhttps://onlinelibrary.wiley.com/doi/10.1111/1744-9987.13730
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-06-28 08:38:20