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Scientific paper - Original scientific paper
The Effect of Surgeon Expertise on the Outcome of Patients with Adrenocortical Carcinoma
Journal of Personalized Medicine, 12 (2022), 1; 100. https://doi.org/10.3390/jpm12010100
(Croatian ACC Study Group) Barač Nekić, Anja; Knežević, Nikola; Zibar Tomšić, Karin; Kraljević, Ivana; Balasko, Annemarie; Škorić Polovina, Tanja; Solak, Mirsala; Dušek, Tina; Kaštelan, Darko

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Barač Nekić, A., Knežević, N., Zibar Tomšić, K., Kraljević, I., Balasko, A., Škorić Polovina, T. ... Kaštelan, D. (2022). The Effect of Surgeon Expertise on the Outcome of Patients with Adrenocortical Carcinoma. Journal of Personalized Medicine, 12. (1). doi: 10.3390/jpm12010100

Barač Nekić, Anja, et al. "The Effect of Surgeon Expertise on the Outcome of Patients with Adrenocortical Carcinoma." Journal of Personalized Medicine, vol. 12, no. 1, 2022. https://doi.org/10.3390/jpm12010100

Barač Nekić, Anja, Nikola Knežević, Karin Zibar Tomšić, Ivana Kraljević, Annemarie Balasko, Tanja Škorić Polovina, Mirsala Solak, Tina Dušek and Darko Kaštelan. "The Effect of Surgeon Expertise on the Outcome of Patients with Adrenocortical Carcinoma." Journal of Personalized Medicine 12, no. 1 (2022). https://doi.org/10.3390/jpm12010100

Barač Nekić, A., et al. (2022) 'The Effect of Surgeon Expertise on the Outcome of Patients with Adrenocortical Carcinoma', Journal of Personalized Medicine, 12(1). doi: 10.3390/jpm12010100

Barač Nekić A, Knežević N, Zibar Tomšić K, Kraljević I, Balasko A, Škorić Polovina T, and sur.. The Effect of Surgeon Expertise on the Outcome of Patients with Adrenocortical Carcinoma. Journal of Personalized Medicine [Internet]. 2022 January 13 [cited 2025 January 14];12(1). doi: 10.3390/jpm12010100

A. Barač Nekić, et al., "The Effect of Surgeon Expertise on the Outcome of Patients with Adrenocortical Carcinoma", Journal of Personalized Medicine, vol. 12, no. 1, January 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:299869. [Accessed: 14 January 2025]

Metadata
Title (english)The Effect of Surgeon Expertise on the Outcome of Patients with Adrenocortical Carcinoma
AuthorAnja Barač Nekić
AuthorNikola Knežević
AuthorKarin Zibar Tomšić
AuthorIvana Kraljević
AuthorAnnemarie Balasko
AuthorTanja Škorić Polovina
AuthorMirsala Solak
AuthorTina Dušek
AuthorDarko Kaštelan
CollaborationCroatian ACC Study Group
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Urology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Urology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Intensive Care
Abstract (english)
Complete surgical removal of adrenocortical carcinoma (ACC) represents the only chance of long-term cure. In this study, we compared the long-term outcomes of ACC patients depending on whether they had adrenal surgery performed in a high-volume (HVC) or in a low-volume (LVC) center. This retrospective study included 49 patients from the Croatian ACC Registry with the European Network for the Study of Adrenal Tumors (ENSAT) stage I–III ACC, of which 35 underwent surgery in a HVC whereas 14 of them were operated in one of the LVCs. Patients operated in the LVCs had a significantly higher rate of ACC recurrence (57.1% vs. 22.9%; p = 0.02). Accordingly, RFS was significantly longer in patients operated on in HVC (p = 0.04). The difference in RFS remained significant after controlling for age, gender, tumor size, Ki-67 index, Weiss score, and type of surgery (HR 4.55; 95% CI 1.16–17.88; p = 0.03). In addition, there is a tendency towards longer DSS in patients in the HVC group compared to those in the LVC group (p = 0.05). These results point to the centralization of adrenal surgery as a key prerequisite for improving the outcomes of ACC patients.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleJournal of Personalized Medicine
Numberingvol. 12, no. 1, 100
e-ISSN2075-4426
DOIhttps://doi.org/10.3390/jpm12010100
URN:NBNurn:nbn:hr:105:299869
Publication2022-01-13
Document URLhttps://www.mdpi.com/2075-4426/12/1/100
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-06-30 09:12:26