Glomerular hyperfiltration is associated with more rapid decline in renal function resulting in chronic kidney disease. It is considered to be an early marker (earlier than albuminuria) of renal impairment in diabetes and hypertension. In prehypertension risk of development albuminuria and chronic kidney disease is not so clear. Since prevalence of prehypertension is high in general population and glomerular hyperfiltration is often found in younger individuals, obese, those with congenital or acquired loss of nephron mass and smokers, it was our aim to investigate whether relationship between glomerular hyperfiltration in prehypertension and other cardiovascular risk factors is independent. Also, in prospective part od the study aim was to investigate whether glomerular hyperfitration leads to chronic kidney disease and cardiovascular disease. Initial enrollment included 1106 examinees from general ruraln population. Prospective dana was analysed for 406 examinees. Zje examinees were devided into 6 groups according to eFR cathegory and differences were analized in crosssectional part of the study while in longitudinal part of the study analized differences between examinees according to their eGFR trend during follow-up period. In follow-up the examinees with lomerular hyperfiltration had statistically the biggest drop in eGFR and the highest cummulative incidence rate of albuminuria. Among prehypertensive group within different eGFR cathegories no significant differences were observed regarding anthropometric, laboratory findings or cardiovascular score risk paramethers. Newly diagnosed hypertension age and abdominal obesity contributed the most, while the risk for new onset hypertension was highes in examinees with bigest annula eGFR drop. No statistically significant differences were observed in anthropometric, laboratory findings or cardiovascular score risk paramethers among groups with different eGFR changes during follow-up period.