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Scientific paper - Original scientific paper
SARS-CoV-2 Omicron Variant in Croatia—Rapid Detection of the First Case and Cross-Border Spread
Pathogens, 11 (2022), 5; 511. https://doi.org/10.3390/pathogens11050511
Ferenčak, Ivana; Obrovac, Mihaela; Žmak, Ljiljana; Kuzle, Josipa; Petrović, Goranka; Vilibić-Čavlek, Tatjana; Jurić, Dragan; Jurić, Anita; Hruškar, Željka; Capak, Krunoslav; Stevanović, Vladimir; Milanović, Maja; Govedarica, Marija; Vujošević, Danijela; Tabain, Irena More authors...

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Ferenčak, I., Obrovac, M., Žmak, Lj., Kuzle, J., Petrović, G., Vilibić Čavlek, T. ... Tabain, I. (2022). SARS-CoV-2 Omicron Variant in Croatia—Rapid Detection of the First Case and Cross-Border Spread. Pathogens, 11. (5). doi: 10.3390/pathogens11050511

Ferenčak, Ivana, et al. "SARS-CoV-2 Omicron Variant in Croatia—Rapid Detection of the First Case and Cross-Border Spread." Pathogens, vol. 11, no. 5, 2022. https://doi.org/10.3390/pathogens11050511

Ferenčak, Ivana, Mihaela Obrovac, Ljiljana Žmak, Josipa Kuzle, Goranka Petrović, Tatjana Vilibić Čavlek, Dragan Jurić, et al. "SARS-CoV-2 Omicron Variant in Croatia—Rapid Detection of the First Case and Cross-Border Spread." Pathogens 11, no. 5 (2022). https://doi.org/10.3390/pathogens11050511

Ferenčak, I., et al. (2022) 'SARS-CoV-2 Omicron Variant in Croatia—Rapid Detection of the First Case and Cross-Border Spread', Pathogens, 11(5). doi: 10.3390/pathogens11050511

Ferenčak I, Obrovac M, Žmak Lj, Kuzle J, Petrović G, Vilibić Čavlek T, and sur.. SARS-CoV-2 Omicron Variant in Croatia—Rapid Detection of the First Case and Cross-Border Spread. Pathogens [Internet]. 2022 April 26 [cited 2024 November 26];11(5). doi: 10.3390/pathogens11050511

I. Ferenčak, et al., "SARS-CoV-2 Omicron Variant in Croatia—Rapid Detection of the First Case and Cross-Border Spread", Pathogens, vol. 11, no. 5, April 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:032233. [Accessed: 26 November 2024]

Metadata
Title (english)SARS-CoV-2 Omicron Variant in Croatia—Rapid Detection of the First Case and Cross-Border Spread
AuthorIvana Ferenčak
AuthorMihaela Obrovac
AuthorLjiljana Žmak
AuthorJosipa Kuzle
AuthorGoranka Petrović
AuthorTatjana Vilibić-Čavlek
AuthorDragan Jurić
AuthorAnita Jurić
AuthorŽeljka Hruškar
AuthorKrunoslav Capak
AuthorVladimir Stevanović
AuthorMaja Milanović
AuthorMarija Govedarica
AuthorDanijela Vujošević
AuthorIrena Tabain
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Medical Microbiology and Parasitology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Abstract (english)
Background: Due to rapid spread, the Omicron variant has become the dominant SARS-CoV-2 variant responsible for infections worldwide. We present the first detection of the Omicron variant in Croatia which resulted in rapid cross-border spreading. ----- Methods: Whole-genome sequencing was performed using the Illumina MiniSeq sequencing system. SARS-CoV-2 lineages were identified using the PANGOLIN and GISAID databases. ----- Results: The first case of the Omicron variant (BA.1.17) emerged in Croatia after a workshop held in Zagreb in November 2021. The patient reported a history of previous COVID-19 and received two doses of an mRNA vaccine. Three additional cases were detected among Croatian participants of the workshop. At the beginning of December, SARS-CoV-2 infection was confirmed in one participant from Montenegro and her husband. Phylogenetic analysis showed that the detected Omicron variants were closely related to the first Croatian case, confirming the connection with the workshop outbreak and rapid cross-border spreading. Subsequent analyses of SARS-CoV-2 positive samples in Croatia showed the rapid introduction of the Omicron variant and depletion of the Delta variant resulting in the fifth pandemic wave. ----- Conclusions: Genomic monitoring and early detection of novel SARS-CoV-2 variants are essential to implement timely epidemiological interventions and reduce further transmission in the population.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titlePathogens
Numberingvol. 11, no. 5, 511
e-ISSN2076-0817
DOIhttps://doi.org/10.3390/pathogens11050511
URN:NBNurn:nbn:hr:105:032233
Publication2022-04-26
Document URLhttps://www.mdpi.com/2076-0817/11/5/511
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-12-08 08:49:55