prikaz prve stranice dokumenta Outbreak of healthcare-associated bacteremia caused by Burkholderia gladioli due to contaminated multidose vials with saline solutions in three Croatian hospitals
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Scientific paper - Original scientific paper
Outbreak of healthcare-associated bacteremia caused by Burkholderia gladioli due to contaminated multidose vials with saline solutions in three Croatian hospitals
International Journal of Infectious Diseases, 121 (2022); 152-156. https://doi.org/10.1016/j.ijid.2022.05.012
Dobrović, Karolina; Mareković, Ivana; Payerl-Pal, Marina; Andrijašević, Nataša; Škrobo, Tea; Košćak, Valentina; Grgurić, Dubravka; Šestan Crnek, Sandra; Janeš, Andrea; Lukić-Grlić, Amarela; Selec, Katarina; Bukovski, Suzana; Čivljak, Rok

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Dobrović, K., Mareković, I., Payerl Pal, M., Andrijašević, N., Škrobo, T., Košćak, V. ... Čivljak, R. (2022). Outbreak of healthcare-associated bacteremia caused by Burkholderia gladioli due to contaminated multidose vials with saline solutions in three Croatian hospitals. International Journal of Infectious Diseases, 121., 152-156. doi: 10.1016/j.ijid.2022.05.012

Dobrović, Karolina, et al. "Outbreak of healthcare-associated bacteremia caused by Burkholderia gladioli due to contaminated multidose vials with saline solutions in three Croatian hospitals." International Journal of Infectious Diseases, vol. 121, 2022, pp. 152-156. https://doi.org/10.1016/j.ijid.2022.05.012

Dobrović, Karolina, Ivana Mareković, Marina Payerl Pal, Nataša Andrijašević, Tea Škrobo, Valentina Košćak, Dubravka Grgurić, et al. "Outbreak of healthcare-associated bacteremia caused by Burkholderia gladioli due to contaminated multidose vials with saline solutions in three Croatian hospitals." International Journal of Infectious Diseases 121 (2022): 152-156. https://doi.org/10.1016/j.ijid.2022.05.012

Dobrović, K., et al. (2022) 'Outbreak of healthcare-associated bacteremia caused by Burkholderia gladioli due to contaminated multidose vials with saline solutions in three Croatian hospitals', International Journal of Infectious Diseases, 121, pp. 152-156. doi: 10.1016/j.ijid.2022.05.012

Dobrović K, Mareković I, Payerl Pal M, Andrijašević N, Škrobo T, Košćak V, and sur.. Outbreak of healthcare-associated bacteremia caused by Burkholderia gladioli due to contaminated multidose vials with saline solutions in three Croatian hospitals. International Journal of Infectious Diseases [Internet]. 2022 August [cited 2024 November 22];121:152-156. doi: 10.1016/j.ijid.2022.05.012

K. Dobrović, et al., "Outbreak of healthcare-associated bacteremia caused by Burkholderia gladioli due to contaminated multidose vials with saline solutions in three Croatian hospitals", International Journal of Infectious Diseases, vol. 121, pp. 152-156, August 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:273149. [Accessed: 22 November 2024]

Metadata
Title (english)Outbreak of healthcare-associated bacteremia caused by Burkholderia gladioli due to contaminated multidose vials with saline solutions in three Croatian hospitals
AuthorKarolina Dobrović
AuthorIvana Mareković
AuthorMarina Payerl-Pal
AuthorNataša Andrijašević
AuthorTea Škrobo
AuthorValentina Košćak
AuthorDubravka Grgurić
AuthorSandra Šestan Crnek
AuthorAndrea Janeš
AuthorAmarela Lukić-Grlić
AuthorKatarina Selec
AuthorSuzana Bukovski
AuthorRok Čivljak
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Infectious Diseases)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Medical Microbiology and Parasitology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Infectology
Abstract (english)
Objectives: Burkholderia gladioli has been associated with infections in patients with cystic fibrosis, chronic granulomatous disease, and other immunocompromising conditions. The aim of this study was to better depict the outbreak of healthcare-associated bacteremia caused by B. gladioli due to exposure to contaminated multidose vials with saline solutions. ----- Methods: An environmental and epidemiologic investigation was conducted by the Infection Prevention and Control Team (IPCT) to identify the source of the outbreak in three Croatian hospitals. ----- Results: During a 3-month period, 13 B. gladioli bacteremia episodes were identified in 10 patients in three Croatian hospitals. At the time of the outbreak, all three hospitals used saline products from the same manufacturer. Two 100-ml multidose vials with saline solutions and needleless dispensing pins were positive for B. gladioli. All 13 bacteremia isolates and two isolates from the saline showed the same antimicrobial susceptibility patterns and pulsed-field gel electrophoresis profile, demonstrating clonal relatedness. ----- Conclusion: When an environmental pathogen causes an outbreak, contamination of intravenous products must be considered. Close communication between the local IPCT and the National Hospital Infection Control Advisory Committee is essential to conduct a prompt and thorough investigation and find the source of the outbreak.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleInternational Journal of Infectious Diseases
Numberingvol. 121, pp. 152-156
p-ISSN1201-9712
DOIhttps://doi.org/10.1016/j.ijid.2022.05.012
URN:NBNurn:nbn:hr:105:273149
Publication2022-08
Document URLhttps://linkinghub.elsevier.com/retrieve/pii/S1201971222002740
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) icon
Created on2022-12-14 09:07:33