Pelvic organ prolapse (POP) is the herniation or prolapse of pelvic organs through the vaginal walls. POP is a very common condition among women, especially of older age, and is one of the main indications for performing gynaecological surgery at present time. The etiology of POP is still not fully understood, but many predisposing risk factors have been associated with the weakening or damage of the endopelvic fascia, such as vaginal delivery, increasing age, obesity, and other conditions leading to increased intraabdominal pressure. Depending on the type and degree of prolapse, women may be symptomatic or completely asymptomatic. We differentiate between three types of POP concerning the involved vaginal segment, namely apical, anterior, and posterior POP. The diagnosis of POP is made after a thorough patient history and physical examination and can be quantified using the POP-Q system. POP is treated with either conservative or surgical management but there are still challenges in determining the best treatment option for POP. The most superior surgical management option for POP is yet to be determined even though successful attempts have been made to repair POP with both native tissue repair and mesh surgery. The issues related to the choice of surgical treatment include associated complications such as mesh erosion, occult incontinence, and recurrence rates, which have led to difficulties in determining the most superior choice for POP treatment.