prikaz prve stranice dokumenta Transcatheter aortic valve therapy
  Download
PDF 4.07 MB
master's thesis
Transcatheter aortic valve therapy
Zagreb: University of Zagreb, School of Medicine, 2021. urn:nbn:hr:105:417136
Negovetić, Paola
University of Zagreb
School of Medicine

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Negovetić, P. (2021). Transcatheter aortic valve therapy (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:417136

Negovetić, Paola. "Transcatheter aortic valve therapy." Master's thesis, University of Zagreb, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:105:417136

Negovetić, Paola. "Transcatheter aortic valve therapy." Master's thesis, University of Zagreb, School of Medicine, 2021. https://urn.nsk.hr/urn:nbn:hr:105:417136

Negovetić, P. (2021). 'Transcatheter aortic valve therapy', Master's thesis, University of Zagreb, School of Medicine, accessed 24 December 2024, https://urn.nsk.hr/urn:nbn:hr:105:417136

Negovetić P. Transcatheter aortic valve therapy [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2021 [cited 2024 December 24] Available at: https://urn.nsk.hr/urn:nbn:hr:105:417136

P. Negovetić, "Transcatheter aortic valve therapy", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:105:417136

Metadata
TitleTranscatheter aortic valve therapy
Title (croatian)Transkatetersko liječenje aortalnog zaliska
AuthorPaola Negovetić
MentorIgor Rudež (mentor)
Committee memberIgor Rudež (predsjednik povjerenstva)
Committee memberTomislav Meštrović (član povjerenstva)
Committee memberJoško Bulum (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
Zagreb
Defense date and country2021-10-18, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract
The aortic valve is a component of the heart’s outflow tract that is responsible for transporting the newly oxygenated blood from the left ventricle to the aorta and from there to the rest of the body. Aortic stenosis is a pathological condition in which narrowing of the aortic valve opening occurs. The clinical symptoms are not noticeable from the beginning but develop later on once the amount of blood being pumped out of the aorta is significantly decreased. Diagnosis of aortic stenosis is confirmed by an echocardiogram. The treatment of choice for aortic stenosis is determined by the severity of the clinical symptoms and the individual characteristics of the patient. For the patients with a severe clinical picture of aortic stenosis, there is an indication for the surgical aortic valve replacement. In the surgical aortic valve replacement, the stenotic valve is removed and replaced with a new valve. However, some patients presenting with a severe aortic stenosis are deemed inoperable or a high risk for surgery. Transcatheter aortic valve implementation is a less invasive choice of therapy for those patients with severe aortic stenosis who were not approved for the surgical aortic valve replacement. In transcatheter aortic valve replacement, a novel valve is implanted within the native pathological valve. By this valve-in-valve implementation, the stenotic valve is being strengthened and made capable of effectively functioning once more.
Abstract (croatian)
Aortni zalistak je sastavni dio izljevnog trakta srca koji je odgovoran za transport krvi svježe obogaćene kisikom iz lijeve klijetke u aortu, te kasnije u ostatak tijela. Stenoza aorte je patološko stanje u kojem dolazi do progresivnog suženja otvora aortnog zaliska. Klinički simptomi često nisu uočljivi od samog početka bolesti, nego se razvijaju tek kasnije kada se količina krvi koja napušta aortu značajno smanji. Dijagnoza aortne stenoze potvrđuje se ultrazvukom srca koji pokazuje patologiju aortnog zaliska te protok krvi iz lijeve klijetke u aortu. Izbor liječenja aortne stenoze određuje se putem procjene ozbiljnosti kliničkih simptoma pacijenta te njihovih individualnim karakteristika. Za bolesnike koji imaju tešku kliničku sliku aortne stenoze postoji indikacija za kiruršku zamjenu patološkog aortnog zaliska. Operativna zamjena aortnog zaliska provodi se tako da se odstrani bolesni zalistak te se ugradi novi. Međutim, neki pacijenti koji imaju dijagnozu teške aortne stenoze smatraju se visokim rizikom za operaciju ili čak neprikladnim za operaciju. Transkateterska implementacija aortnog zaliska manje je invazivan izbor terapije za one pacijente s dijagnozom teške stenoze aorte kojima nije odobrena kirurška zamjena aortnog zaliska. Kod transkateterske zamjene aortnog zaliska, novi zalistak se implantira unutar originalnog patološkog zaliska. Ovom vrstom implementacije, stenotični zalistak je ojačan i ponovno osposobljen za učinkovito funkcioniranje.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:105:417136
Study programmeTitle: Medicine (in English language)
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2022-12-20 12:11:18