Valvular heart diseases are associated with ageing and its indicator is an increase of prevalence with age. General population is getting older, so the rise in the number of people diagnosed with valvular heart disease is expected together with the increased burden on the healthcare system. The most common valvular heart diseases are aortic stenosis and mitral regurgitation. The prevalence of the aortic stenosis in the general population is 0.4% and in the group ˃ 65 years is 1.7%. The prevalence of mitral prolapse, which is the most common cause of the mitral regurgitation that has to undergo surgery, is 2-3% in the general population. Surgery is the treatment of choice. An alternative therapeutic option is transcatheter intervention, such as TAVI, which is used for the treatment of the aortic stenosis. Medical therapy is used for the symptom control. Less common degenerative heart valve diseases are those of tricuspid and pulmonary valve. The tricuspid valve is mostly affected by other heart diseases, so usually secondary tricuspid regurgitation is diagnosed. Degenerative processes rarely have an effect on the pulmonary valve, but the interest regarding pulmonary valve has increased during the last years. Multiple valvular heart diseases are highly prevalent, and they represent an emerging challenge. When discussing treatment options, it is important to assess the effect that each valve disease has on haemodynamics and how they interact. The combination of the aortic stenosis and the mitral regurgitation is the most significant one in degenerative valve diseases.