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master's thesis
Lobularni karcinom dojke
Zagreb: University of Zagreb, School of Medicine, 2022. urn:nbn:hr:105:500738
Ceković, Darko
University of Zagreb
School of Medicine
Department of Pathology

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Ceković, D. (2022). Lobularni karcinom dojke (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:500738

Ceković, Darko. "Lobularni karcinom dojke." Master's thesis, University of Zagreb, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:105:500738

Ceković, Darko. "Lobularni karcinom dojke." Master's thesis, University of Zagreb, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:105:500738

Ceković, D. (2022). 'Lobularni karcinom dojke', Master's thesis, University of Zagreb, School of Medicine, accessed 26 December 2024, https://urn.nsk.hr/urn:nbn:hr:105:500738

Ceković D. Lobularni karcinom dojke [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2022 [cited 2024 December 26] Available at: https://urn.nsk.hr/urn:nbn:hr:105:500738

D. Ceković, "Lobularni karcinom dojke", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:105:500738

Metadata
TitleLobularni karcinom dojke
Title (english)Lobular breast cancer
AuthorDarko Ceković
MentorDavor Tomas (mentor)
Committee memberMonika Ulamec (predsjednik povjerenstva)
Committee memberLovorka Batelja-Vuletić (član povjerenstva)
Committee memberDavor Tomas (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Pathology)
Zagreb
Defense date and country2022-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pathology
Abstract
Lobularni karcinom dojke (drugi naziv: invazivni lobularni karcinom) je vrsta raka dojke koji se razvija u mliječnim žlijezdama (lobulima) dojke. Lobularni karcinom je drugi najčešći tip raka dojke; na njega otpada otprilike 10 do 15 posto svih invazivnih karcinoma dojke. Može se prezentirati različitim simptomima, kao što su oteklina cijele ili jednog dijela dojke, iritacija kože, stvaranje malih rupica na koži (može podsjećati na narančinu koru), bol u dojci ili u području bradavice, iscjedak iz dojke, crvenilo, zadebljanje ili ljuštenje kože dojke ili bradavice te pojava kvržice ili otekline u području pazuha. Prvi korak u dijagnosticiranju lobularnog karcinoma dojke jest uzimanje detaljne anamneze i klinički pregled pacijenta, nakon čega slijede radiološke dijagnostičke metode, kao što su mamografija, ultrazvuk dojke i magnetna rezonancija. Ako se pomoću tih metoda uoči abnormalnost, izvodi se biopsija dojke širokom iglom radi potvrde nalaza. Prognoza i liječenje lobularnog karcinoma dojke ovisi u kojem stadiju je bolest dijagnosticirana, pri čemu se koristi TNM klasifikacijski sustav (stadiji 1 - 4). Metode liječenja uključuju kiruršku resekciju (bilo cijele dojke ili samo dijela u kojem se nalazi tumor), kemoterapiju i radioterapiju, hormonsku terapiju, ciljanu terapiju te imunoterapiju.
Abstract (english)
Lobular breast cancer (also called invasive lobular carcinoma) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast. It is the second most common type of breast cancer, accounting for 10 to 15 percent of all invasive breast cancers. It presents with a wide variety of symptoms, including swelling of all or part of the breast, skin irritation, skin dimpling (sometimes looking like an orange peel), breast or nipple pain, nipple discharge, redness, scaliness or thickening of the nipple or breast skin or a lump or swelling of the underarm area. The first step in diagnosing lobular breast cancer is patient examination and detailed history taking, which is followed by radiological imaging, including mammography, ultrasound and magnetic resonance imaging (MRI). If an abnormality is detected, core needle biopsy is performed to confirm the findings. The prognosis and treatment of lobular breast cancer depends on the stage of the disease, which is primarily determined by using the TNM staging system (stages 1 - 4). Methods of treatment include surgical resection (either the whole breast or exclusively the part where the tumor is located), chemotherapy and radiotherapy, hormonal therapy, targeted therapy and immunotherapy.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:500738
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-01-04 10:49:51