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master's thesis
Serozni karcinom jajnika niskog gradusa
Zagreb: University of Zagreb, School of Medicine, 2022. urn:nbn:hr:105:548689
Grudić, Karlo
University of Zagreb
School of Medicine
Department of Gynecology and Obstetrics

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Grudić, K. (2022). Serozni karcinom jajnika niskog gradusa (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:548689

Grudić, Karlo. "Serozni karcinom jajnika niskog gradusa." Master's thesis, University of Zagreb, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:105:548689

Grudić, Karlo. "Serozni karcinom jajnika niskog gradusa." Master's thesis, University of Zagreb, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:105:548689

Grudić, K. (2022). 'Serozni karcinom jajnika niskog gradusa', Master's thesis, University of Zagreb, School of Medicine, accessed 29 April 2024, https://urn.nsk.hr/urn:nbn:hr:105:548689

Grudić K. Serozni karcinom jajnika niskog gradusa [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2022 [cited 2024 April 29] Available at: https://urn.nsk.hr/urn:nbn:hr:105:548689

K. Grudić, "Serozni karcinom jajnika niskog gradusa", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:105:548689

Metadata
TitleSerozni karcinom jajnika niskog gradusa
Title (english)Low grade serous ovarian cancer
AuthorKarlo Grudić
MentorJoško Lešin (mentor)
Committee memberGoran Vujić (predsjednik povjerenstva)
Committee memberDinka Pavičić Baldani (član povjerenstva)
Committee memberJoško Lešin (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Gynecology and Obstetrics)
Zagreb
Defense date and country2022-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Gynecology and Obstetrics
Abstract
Serozni kacinom jajnika niskog gradusa je podvrsta karcinoma ovarija kojeg karakterizira manje agresivno ponašanje i bolji klinički ishod od drugih karcinoma ovarija. Bolest se najčešće dijagnosticira ultrazvučno, CT-om ili MR-om. Relativno je kemorezistentan i zbog toga je citoreduktivna operacija zlatni standard u ranim stadijima bolesti. Pacijentice sa višim stadijima bolesti nakon primarne operacije primaju adjuvantnu terapiju. Neoadjuvantna kemoterapija se koristi kod uznapredovale bolesti u kojoj zbog stanja pacijentice operacija nije moguća. Za održavanje remisije se u terapiji primjenjuje se i hormonska terapija i ciljana terapija poput anti-VEGF protutijela bevacizumab. U ovom istraživanju pomoću baze podataka istražujemo ishode liječenja, OS i PFS kod primjene raznih modaliteta kemoterapije i operativnog liječenja i njihov utjecaj na konačnu prognozu kod pacijentica.
Abstract (english)
Low-grade serous ovarian cancer is a subtype of ovarian cancer characterized by less aggressive behaviour and a better clinical outcome than other ovarian cancers. The disease is most commonly diagnosed by ultrasound, CT, or MR. It is relatively chemoresistant and therefore cytoreductive surgery is the gold standard in the early stages of the disease. Patients with higher stages of the disease receive adjuvant therapy after primary surgery. Neoadjuvant chemotherapy is used in advanced disease in which surgery is not possible due to the patient's condition. To maintain remission, both hormone therapy and targeted therapy such as the anti-VEGF antibody bevacizumab are used in therapy. In this study, we use a database to investigate treatment outcomes, OS and PFS in the application of various modalities of chemotherapy and surgical treatment and their impact on the final prognosis in patients.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:548689
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-01-09 10:02:45