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master's thesis
Kožni oblici eritemskog lupusa
Zagreb: University of Zagreb, School of Medicine, 2014. urn:nbn:hr:105:551545
Šolčić, Lidija
University of Zagreb
School of Medicine
Department of Dermatology

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Šolčić, L. (2014). Kožni oblici eritemskog lupusa (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:551545

Šolčić, Lidija. "Kožni oblici eritemskog lupusa." Master's thesis, University of Zagreb, School of Medicine, 2014. https://urn.nsk.hr/urn:nbn:hr:105:551545

Šolčić, Lidija. "Kožni oblici eritemskog lupusa." Master's thesis, University of Zagreb, School of Medicine, 2014. https://urn.nsk.hr/urn:nbn:hr:105:551545

Šolčić, L. (2014). 'Kožni oblici eritemskog lupusa', Master's thesis, University of Zagreb, School of Medicine, accessed 29 December 2024, https://urn.nsk.hr/urn:nbn:hr:105:551545

Šolčić L. Kožni oblici eritemskog lupusa [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2014 [cited 2024 December 29] Available at: https://urn.nsk.hr/urn:nbn:hr:105:551545

L. Šolčić, "Kožni oblici eritemskog lupusa", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2014. Available at: https://urn.nsk.hr/urn:nbn:hr:105:551545

Metadata
TitleKožni oblici eritemskog lupusa
Title (english)Cutaneous forms of lupus erythematosus
AuthorLidija Šolčić
MentorBranka Marinović (mentor)
Committee memberRomana Čeović (predsjednik povjerenstva)
Committee memberALEKSANDRA BASTA-JUZBAŠIĆ (član povjerenstva)
Committee memberBranka Marinović (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Dermatology)
Zagreb
Defense date and country2014-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Dermatovenerology
Abstract
Eritemski lupus (LE) je kronična, autoimunosna bolest koja uključuje širok spektar simptoma. Podijeljena je na sustavni oblik – SLE i kožni oblik – CLE koji se mogu pojaviti zajedno ili odvojeno. Kuhn i suradnici su 2003. godine razvili modificirani klasifikacijski sustav koji se naziva „Düsseldorfska klasifikacija kožnog eritemskog lupusa 2003“. Prema toj klasifikaciji CLE se dijeli na akutni kožni eritemski lupus (ACLE), subakutni CLE (SCLE), kronični CLE (CCLE) kod kojeg je klasični diskoidni LE (DLE) najčešći oblik, lupus eritematosus tumidus (LET) kao intermitentni podtip CLE-a (ICLE) i bulozne kožne lezije povezane sa LE (BLE). Svi podtipovi kožnih oblika eritemskog lupusa su definirani specifičnim kliničkim simptomima, prosječnim trajanjem simptoma te histološkim i serološkim nalazima, međutim vrlo često se klinička obilježja preklapaju. Pacijenti sa kožnim oblicima eritemskog lupusa imaju dobro definirane kožne lezije, često na mjestima izloženima suncu. Bolest se uglavnom očituje kroničnim tijekom i relapsima izazvanima izlaganjem sunčevu svjetlu. Vrlo je važno potvrditi dijagnozu CLE-a histopatološki biopsijom jer postoji nekoliko diferencijalnih dijagnoza te redovito kontrolirati bolesnika zbog mogućnosti prelaska u sistemni oblik bolesti. Liječenje CLE-a uključuje zaštitu od sunca, lokalnu terapiju i sistemsku terapiju.
Abstract (english)
Lupus Erythematosus (LE) is a chronic, autoimmune disease that includes a broad spectrum of symptoms. It is divided into one systemic form – SLE and one cutaneous form – CLE. They can occur both together and separately. In 2003 Kuhn and al. developed a modified classification system named „Düsseldorf Classification of Cutaneous Lupus Erythematosus 2003“. The classification system divided CLE to acute CLE (ACLE), subacute CLE (SCLE), chronic CLE (CCLE) where discoid LE (DLE) is the most common form, lupus erythematosus tumidus (LET) as the intermittent subtype of CLE (ICLE) and bullous lesions in lupus erythematosus (BLE). All subsets are defined by clinical symptoms, average duration of symptoms and histological and serological findings, although, the subtypes can have overlapping clinical features. CLE patients display well-defined skin lesions, often in sun-exposed areas. The disease often has a chronic and relapsing course that can be induced or aggravated by UV light. It is important to confirm a CLE diagnosis histopathologically by a biopsy and in that there are several differential diagnoses and regular follow-up is important because progression to SLE can occur. CLE treatment combines sun protection, topical therapies, and systemic agents.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:551545
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2016-03-14 13:44:48