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master's thesis
Tromboembolijske komplikacije i profilaksa kod velikih abdominalnih operacija
Zagreb: University of Zagreb, School of Medicine, 2022. urn:nbn:hr:105:036091
Lacković, Margareta
University of Zagreb
School of Medicine
Department of Anaesthesiology, Resuscitation and Intensive Care in Surgical Specialities

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Lacković, M. (2022). Tromboembolijske komplikacije i profilaksa kod velikih abdominalnih operacija (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:036091

Lacković, Margareta. "Tromboembolijske komplikacije i profilaksa kod velikih abdominalnih operacija." Master's thesis, University of Zagreb, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:105:036091

Lacković, Margareta. "Tromboembolijske komplikacije i profilaksa kod velikih abdominalnih operacija." Master's thesis, University of Zagreb, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:105:036091

Lacković, M. (2022). 'Tromboembolijske komplikacije i profilaksa kod velikih abdominalnih operacija', Master's thesis, University of Zagreb, School of Medicine, accessed 25 April 2024, https://urn.nsk.hr/urn:nbn:hr:105:036091

Lacković M. Tromboembolijske komplikacije i profilaksa kod velikih abdominalnih operacija [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2022 [cited 2024 April 25] Available at: https://urn.nsk.hr/urn:nbn:hr:105:036091

M. Lacković, "Tromboembolijske komplikacije i profilaksa kod velikih abdominalnih operacija", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:105:036091

Metadata
TitleTromboembolijske komplikacije i profilaksa kod velikih abdominalnih operacija
Title (english)Thromboembolic complications and prophylaxis in patients undergoing major abdominal surgery
AuthorMargareta Lacković
MentorTomislav Radočaj (mentor)
Committee memberMarinko Vučić (predsjednik povjerenstva)
Committee memberDinko Tonković (član povjerenstva)
Committee memberTomislav Radočaj (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Anaesthesiology, Resuscitation and Intensive Care in Surgical Specialities)
Zagreb
Defense date and country2022-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Anesthesiology and Reanimatology
Abstract
Medicinski pojam tromboembolijske komplikacije podrazumijeva dva entiteta: duboku vensku trombozu i plućnu emboliju. Duboka venska tromboza predstavlja okluziju dubokih vena, najčešće nogu, trombom. Plućna embolija je stanje nastalo iznenadnim smještanjem tromba u dijelu plućne arterije s posljedičnom opstrukcijom plućnog krvotoka. Do tromboembolijskih incidenata dolazi zbog trijasa čimbenika: venske staze, vaskularnog oštećenja i hiperkoagulabilnosti. Najčešći rizični čimbenici su mirovanje, imobilizacija, kirurški zahvat i kirurška trauma što dovodi do krvne staze unutar venskog sustava. Tromboprofilaksa kod velikih abdominalnih operacija indicirana je u bolesnika koji imaju neki od rizičnih čimbenika: imobilizacija, dob, pretilost, maligna bolest, trudnoća, prethodne tromboembolijske komplikacije ili pozitivna obiteljska anamneza. Profilaksa koja se provodi heparinom, značajno smanjuje rizik od tromboembolijskih komplikacija. Preporuča se intravenska primjena nefrakcioniranog heparina ili supkutana primjena niskomolekularnog heparina. Također, smjernice uključuju i nove oralne antikoagulanse. Od nefarmakoloških metoda koriste se što ranija mobilizacija pacijenta, kompresivne čarape te intermitentna pneumatska kompresija donjih ekstremiteta.
Abstract (english)
The medical term for thromboembolic complication includes two entities: deep vein thrombosis and pulmonary embolism. Deep vein thrombosis is the occlusion of deep veins, most often the legs, by a thrombus. Pulmonary embolism is a condition caused by the sudden placement of a blood clot in a part of the pulmonary artery with consequent obstruction of the pulmonary blood flow. Thromboembolic incidents occur due to a triad of factors: venous pathways, vascular damage, and hypercoagulability. The most common risk factors are rest, immobilization, surgery, and surgical trauma leading to blood flow within the venous system. Thromboprophylaxis in major abdominal surgery is indicated in patients who have some of the risk factors: immobilization, age, obesity, malignancy, pregnancy, previous thromboembolic complications, positive family history, etc. Heparin prophylaxis significantly reduces the risk of thromboembolic complications. Intravenous administration of unfractionated heparin or subcutaneous administration of low molecular weight heparin is recommended. Also, the guidelines include new oral anticoagulants. The non-pharmacological methods include the earliest possible mobilization of the patient, compression stockings and intermittent pneumatic compression of lower limbs.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:036091
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-01-17 11:52:38