Epilepsy is the most common chronic neurological condition, affecting more than 50 million people worldwide. In Croatia, around 40 thousand people are living with epilepsy. Epilepsy in pregnancy poses a special problem. The disease itself can harm both the mother and the fetus and, additionally, the use of antiepileptic drugs during pregnancy is associated with higher risk pregnancies, adverse perinatal outcomes and higher risk of congenital malformations. Because of that, a multidisciplinary approach is essential in the monitoring of these patients. In this opservational retrospective study, we observed 53 pregnancies from women on antiepileptic therapy and the outcomes of their pregnancies, as well as opstetrical complications and perinatal outcomes. The main goal of this study was to determine the differences between the group of women on monotherapy as opposed to the group on polytherapy. 60.38% of women were on monotherapy and 39.62% were on polytherapy. A slightly higher incidences of elective cesarean section (28.57% vs. 15.62%) and epileptic seizures during pregnancy (33.3% nasuprot 25%) were observed in the group on polytherapy. There were no intrauterine fetal death nor children born with congenital malformations during the study. It was shown that the incidence of seizures in the year preceeding conception was a good indicator of the incidence of seizures during pregnancy. For that reason, planning for pregnancy in women with epilepsy of generative age is of great importance, so the patient can put the disease under control with the lowest number and dose of antiepileptic drugs.