Intracranial hemorrhage is defined as the pathologic accumulation of blood within the cranial cavity. It occurs mainly in prematures, but it can also occur in full-term infants. It is one of the most common brain injuries in newborns, and also the most important cause of death in newborns. It represents a major challenge to neonatal medicine due to the serious neurodevelopmental consequences it can lead to. The frequency and type of intracranial hemorrhage vary with gestational age. The more immature is the newborn, the higher is the frequency of bleeding. Intracranial hemorrhage in neonates can occur due to congenital and acquired disorders. The most common causes are hypoxia, changes in perfusion in cerebral blood vessels and mechanical trauma during vaginal delivery. Clinical types of intracranial hemorrhage in neonates are epidural hemorrhage, subdural hemorrhage, subarachnoid hemorrhage, periventricular hemorrhage with extension to intraventricular hemorrhage, intraparenchymal cerebral hemorrhage, and cerebellar hemorrhage. Subdural and intraparenchymal cerebral hemorrhages are more common in full-term infants, while subarachnoid, intraventricular, and cerebellar hemorrhages are more common in preterm infants. The clinical presentation is generally nonspecific and must be confirmed by radiological imaging methods such as ultrasound, computed tomography and magnetic resonance imaging. Treatment of intracranial hemorrhage in neonates consists of intensive monitoring and conservative approach and only a small number of neonates require neurosurgical intervention. The prognosis of intracranial hemorrhage depends on the maturity of the newborn's brain, the localization and extent of the hemorrhage, the underlying etiology and the presence of other disorders. Early recognition of symptoms and signs of intracranial hemorrhage is crucial in preventing further progression and detecting early complications.