AIM: The aim of this study was to examine the effect of dilatation of atherosclerotic renal artery stenosis (RAS) by endovascular intervention on augmentation index (AIx) and aortic pulse wave velocity (PWVao). MATERIALS AND METHODS: Thirty-one patients, 15 (48,4%) male and 16 (51,6%) female, average age 64,3 ± 10,3 years, with diagnosis of hemodynamically significant atherosclerotic RAS were included in this study. All patients had digital subtraction angiography (DSA) of renal arteries performed before the endovascular intervention. In all patients AIx and PWVao were noninvasively measured, before and 6 months after the endovascular treatment, using Arteriograph (TensioMedTM, Budapest, Hungary). RESULTS: A statistically significant decrease of AIx (-12,3 ± 12,2%, P <0,001) and PWVao (-1,1 ± 2,0 m / s, P = 0,005) was registered in the 6-month control period after the endovascular intervention, which proved a positive correlation between interventional procedure and a statistically significant decrease of AIx (P <0,001) and PWVao (P = 0,002). CONCLUSIONS: Endovascular renal intervention, together with antihypertensive medication, in hemodynamically significant atherosclerotic RAS of 60% or more, induces changes in AIx and PWVao value, leading to their significant decrease in the control period of 6 months after the procedure. Further investigations are required to include a larger number of patients and longer follow-up period in order to further evaluate and validate obtained results.