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master's thesis
Radiološki dijagnostički postupak kod inflamatornog karcinoma dojke
Zagreb: University of Zagreb, School of Medicine, 2015. urn:nbn:hr:105:541907
Varjačić, Mateja
University of Zagreb
School of Medicine
Department of Radiology

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Varjačić, M. (2015). Radiološki dijagnostički postupak kod inflamatornog karcinoma dojke (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:541907

Varjačić, Mateja. "Radiološki dijagnostički postupak kod inflamatornog karcinoma dojke." Master's thesis, University of Zagreb, School of Medicine, 2015. https://urn.nsk.hr/urn:nbn:hr:105:541907

Varjačić, Mateja. "Radiološki dijagnostički postupak kod inflamatornog karcinoma dojke." Master's thesis, University of Zagreb, School of Medicine, 2015. https://urn.nsk.hr/urn:nbn:hr:105:541907

Varjačić, M. (2015). 'Radiološki dijagnostički postupak kod inflamatornog karcinoma dojke', Master's thesis, University of Zagreb, School of Medicine, accessed 18 December 2024, https://urn.nsk.hr/urn:nbn:hr:105:541907

Varjačić M. Radiološki dijagnostički postupak kod inflamatornog karcinoma dojke [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2015 [cited 2024 December 18] Available at: https://urn.nsk.hr/urn:nbn:hr:105:541907

M. Varjačić, "Radiološki dijagnostički postupak kod inflamatornog karcinoma dojke", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:105:541907

Metadata
TitleRadiološki dijagnostički postupak kod inflamatornog karcinoma dojke
Title (english)Imaging of inflammatory breast cancer
AuthorMateja Varjačić
MentorMaja Prutki (mentor)
Committee memberJasminka Jakić-Razumović (predsjednik povjerenstva)
Committee memberMilan Radoš (član povjerenstva)
Committee memberMaja Prutki (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Radiology)
Zagreb
Defense date and country2015-07-15, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Radiology
Abstract
Inflamatorni karcinom dojke je rijedak i vrlo agresivan tip tumora dojke. Očituje se eritematoznom i edematoznom dojkom sa ili bez palpabilnih masa i potpuno razvijenom kliničkom slikom unutar 3 mjeseca od početka prvih simptoma. Čak 55–85% bolesnica pri postavljanu dijagnoze već ima metastaze u aksilarne ili supraklavikularne limfne čvorove, a 20-40% ih ima i udaljene metastaze najčešće u kosti, jetru, pluća ili mozak. Ukupno 5-godišnje preživljenje, unatoč agresivnoj terapiji, iznosi samo 30-40%. Zbog svega navedenog, vrlo je važno brzo i precizno postavljanje dijagnoze pri čemu radiološki dijagnostički postupci imaju veliku ulogu. Većina bolesnica sa inflamatornim karcinomom ima mamografski guste dojke koje, u kombinaciji sa edemom, daju ograničene i suptilne mamografski vidljive promjene. Ultrazvuk (UZV) je vrlo korisna, dopunska dijagnostička metoda koja bolje prikazuje inflamatorno promijenjene dojke, eventualne tumorske mase i uvećane regionalne limfne čvorove. Biopsija je nužna za dokaz malignosti, a najčešće se izvodi pod kontrolom UZV-a. Ako klinički simptomi ukazuju na inflamatorni karcinom, a mamografija i UZV ne mogu prikazati tumor niti odrediti mjesto biopsije, potrebno je učiniti magnetnu rezonanciju dojke.
Abstract (english)
Inflammatory breast cancer is a rare and very aggressive type of breast tumor. It is characterized by rapid progression, erythema and edema of the breast with or without underlying palpable mass. At presentation, 50-85% of patients will have metastases to axillary and supraclavicular lymph nodes, and 20- 40 % of them will also have distant metastases to lungs, liver, bone or brain. Overall 5-year survival, despite aggressive therapy, is still very low. Because of all of the above, imaging is very important part of managing inflammatory breast cancer. Most of the patients with inflammatory breast cancer have dense breast tissue, which, in combination with edema, may lead to poor imaging findings on mammography. Ultrasonography is good additional diagnostic method. It is better in identification of a focal breast abnormality and regional nodal involvement. Biopsy is necessary to prove malignancy and ultrasound guided biopsy is the most common technique. If clinical signs suggesting inflammatory breast cancer and mammography and ultrasound can not detect primary breast lesion, MR imaging is indicated.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:541907
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2016-04-13 10:50:17