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Scientific paper - Original scientific paper
COVID-19 and Pulmonary Thrombosis - An Unresolved Clinical Puzzle: A Single-Center Cohort Study
Journal of Clinical Medicine, 11 (2022), 23; 7049. https://doi.org/10.3390/jcm11237049
Močibob, Loris; Šušak, Frano; Šitum, Maja; Višković, Klaudija; Papić, Neven; Vince, Adriana

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Močibob, L., Šušak, F., Šitum, M., Višković, K., Papić, N. & Vince, A. (2022). COVID-19 and Pulmonary Thrombosis - An Unresolved Clinical Puzzle: A Single-Center Cohort Study. Journal of Clinical Medicine, 11. (23). doi: 10.3390/jcm11237049

Močibob, Loris, et al. "COVID-19 and Pulmonary Thrombosis - An Unresolved Clinical Puzzle: A Single-Center Cohort Study." Journal of Clinical Medicine, vol. 11, no. 23, 2022. https://doi.org/10.3390/jcm11237049

Močibob, Loris, Frano Šušak, Maja Šitum, Klaudija Višković, Neven Papić and Adriana Vince. "COVID-19 and Pulmonary Thrombosis - An Unresolved Clinical Puzzle: A Single-Center Cohort Study." Journal of Clinical Medicine 11, no. 23 (2022). https://doi.org/10.3390/jcm11237049

Močibob, L., et al. (2022) 'COVID-19 and Pulmonary Thrombosis - An Unresolved Clinical Puzzle: A Single-Center Cohort Study', Journal of Clinical Medicine, 11(23). doi: 10.3390/jcm11237049

Močibob L, Šušak F, Šitum M, Višković K, Papić N, Vince A. COVID-19 and Pulmonary Thrombosis - An Unresolved Clinical Puzzle: A Single-Center Cohort Study. Journal of Clinical Medicine [Internet]. 2022 November 29 [cited 2024 May 03];11(23). doi: 10.3390/jcm11237049

L. Močibob, F. Šušak, M. Šitum, K. Višković, N. Papić and A. Vince, "COVID-19 and Pulmonary Thrombosis - An Unresolved Clinical Puzzle: A Single-Center Cohort Study", Journal of Clinical Medicine, vol. 11, no. 23, November 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:241408. [Accessed: 03 May 2024]

Metadata
Title (english)COVID-19 and Pulmonary Thrombosis - An Unresolved Clinical Puzzle: A Single-Center Cohort Study
AuthorLoris Močibob
AuthorFrano Šušak
AuthorMaja Šitum
AuthorKlaudija Višković
AuthorNeven Papić
AuthorAdriana Vince
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Infectious Diseases)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Infectology
Abstract (english)
Pulmonary thrombosis (PT) is a frequent complication of COVID-19. However, the risk factors, predictive scores, and precise diagnostic guidelines on indications for CT pulmonary angiography (CTPA) are still lacking. This study aimed to analyze the clinical and laboratory characteristics associated with PT in patients with COVID-19. We conducted a cohort study of consecutively hospitalized adult patients with COVID-19 who underwent CTPA at the University Hospital for Infectious Diseases in Zagreb, Croatia between 1 April and 31 December 2021. Of 2078 hospitalized patients, 575 (27.6%) underwent CTPA. PT was diagnosed in 178 (30.9%) patients (69.6% males, median age of 61, IQR 50–69 years). The PT group had a higher CRP, LDH, D-dimer, platelets, and CHOD score. PT was more frequent in patients requiring ≥15 L O2/min (25.0% vs. 39.7%). In multivariable analysis, only D-dimer ≥ 1.0 mg/L (OR 1.78, 95%CI 1.12–2.75) and O2 ≥ 15 L (OR 1.89, 95%CI 1.26–2.84) were associated with PT. PT was not associated with in-hospital mortality. In conclusion, our data confirmed a high incidence of PT in hospitalized patients with COVID-19, however, no correlation with traditional risk factors and mortality was found. CTPA should be performed in patients requiring high-flow supplemental oxygen or those with increased D-dimer levels.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleJournal of Clinical Medicine
Numberingvol. 11, no. 23, 7049
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm11237049
URN:NBNurn:nbn:hr:105:241408
Publication2022-11-29
ProjectNumber: UIP-2019-04-7194
Title (croatian): Uloga imunih semaforina u nealkoholnoj masnoj bolesti jetre i sepsi
Title (english): The role of immune semaphorins in NAFLD and sepsis
Acronym: SepsisFAT
Leader: Neven Papić
Jurisdiction: Croatia
Funding stream: UIP
Document URLhttps://www.mdpi.com/2077-0383/11/23/7049
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-05-17 14:06:37