prikaz prve stranice dokumenta Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms
Embargo period 2024-08-01
Scientific paper - Original scientific paper
Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms
Journal of Chemotherapy, 35 (2022), 4; 281-291. https://doi.org/10.1080/1120009X.2022.2104294
Bedenić, Branka; Likić, Saša; Žižek, Marta; Bratić, Vesna; D'Onofrio, Valentino; Cavrić, Gordana; Pavliša, Gordana; Vodanović, Marijo; Gyssens, Inge; Barišić, Ivan

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Bedenić, B., Likić, S., Žižek, M., Bratić, V., D'Onofrio, V., Cavrić, G. ... Barišić, I. (2022). Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms. Journal of Chemotherapy, 35. (4), 281-291. doi: 10.1080/1120009X.2022.2104294

Bedenić, Branka, et al. "Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms." Journal of Chemotherapy, vol. 35, no. 4, 2022, pp. 281-291. https://doi.org/10.1080/1120009X.2022.2104294

Bedenić, Branka, Saša Likić, Marta Žižek, Vesna Bratić, Valentino D'Onofrio, Gordana Cavrić, Gordana Pavliša, Marijo Vodanović, Inge Gyssens and Ivan Barišić. "Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms." Journal of Chemotherapy 35, no. 4 (2022): 281-291. https://doi.org/10.1080/1120009X.2022.2104294

Bedenić, B., et al. (2022) 'Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms', Journal of Chemotherapy, 35(4), pp. 281-291. doi: 10.1080/1120009X.2022.2104294

Bedenić B, Likić S, Žižek M, Bratić V, D'Onofrio V, Cavrić G, and sur.. Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms. Journal of Chemotherapy [Internet]. 2022 July [cited 2024 April 28];35(4):281-291. doi: 10.1080/1120009X.2022.2104294

B. Bedenić, et al., "Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms", Journal of Chemotherapy, vol. 35, no. 4, pp. 281-291, July 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:463505. [Accessed: 28 April 2024]

Metadata
Title (english)Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms
AuthorBranka Bedenić
AuthorSaša Likić
AuthorMarta Žižek
AuthorVesna Bratić
AuthorValentino D'Onofrio
AuthorGordana Cavrić
AuthorGordana Pavliša
AuthorMarijo Vodanović
AuthorInge Gyssens
AuthorIvan Barišić
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Medical Microbiology and Parasitology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Medical Microbiology
Abstract (english)
Blood samples were collected alongside with routine blood cultures (BC) from patients with suspected sepsis, to evaluate the prevalence of different causative agents in patients with bacteraemia. Among 667 blood samples, there were 122 positive BC (18%). Haemoglobin content, platelet number, and systolic blood pressure values were significantly lower in patients with positive BC, whereas serum lactate levels, CRP, creatinine and urea content were significantly higher in patients with positive BC. The rate of multidrug (MDR) or extensively drug resistant (XDR) bacteria was 24% (n = 29): Klebsiella pneumoniae (9), Pseudomonas aeruginosa (9), Acinetobacter baumannii (4), Escherichia coli (1), vancomycin resistant Enterococcus spp (VRE) (3), and methicillin-resistant Staphylococcus aureus MRSA (3). The dominant resistance mechanisms were the production of extended-spectrum β-lactamases, OXA-48 carbapenemase, and colistin resistance in K. pneumoniae, VIM metallo-β-lactamases in P. aeruginosa and OXA-23-like oxacillinases in A. baumannii. The study revealed high rate of MDR strains among positive BCs in Zagreb, Croatia.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleJournal of Chemotherapy
Numberingvol. 35, no. 4, pp. 281-291
p-ISSN1120-009X
e-ISSN1973-9478
DOIhttps://doi.org/10.1080/1120009X.2022.2104294
URN:NBNurn:nbn:hr:105:463505
Publication2022-07
Document URLhttps://www.tandfonline.com/doi/full/10.1080/1120009X.2022.2104294
Type of resourceText
Access conditionsEmbargoed access
Embargo expiration date: 2024-08-01
Terms of useLicence In copyright icon
Created on2023-08-28 08:18:58