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master's thesis
Učestalost komponenata metaboličkog sindroma i masne jetre u bolesnika s teškom bakterijskom infekcijom
Zagreb: University of Zagreb, School of Medicine, 2023. urn:nbn:hr:105:575985
Krüger, Sanja
University of Zagreb
School of Medicine
Department of Infectious Diseases

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Krüger, S. (2023). Učestalost komponenata metaboličkog sindroma i masne jetre u bolesnika s teškom bakterijskom infekcijom (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:575985

Krüger, Sanja. "Učestalost komponenata metaboličkog sindroma i masne jetre u bolesnika s teškom bakterijskom infekcijom." Master's thesis, University of Zagreb, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:105:575985

Krüger, Sanja. "Učestalost komponenata metaboličkog sindroma i masne jetre u bolesnika s teškom bakterijskom infekcijom." Master's thesis, University of Zagreb, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:105:575985

Krüger, S. (2023). 'Učestalost komponenata metaboličkog sindroma i masne jetre u bolesnika s teškom bakterijskom infekcijom', Master's thesis, University of Zagreb, School of Medicine, accessed 04 May 2024, https://urn.nsk.hr/urn:nbn:hr:105:575985

Krüger S. Učestalost komponenata metaboličkog sindroma i masne jetre u bolesnika s teškom bakterijskom infekcijom [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2023 [cited 2024 May 04] Available at: https://urn.nsk.hr/urn:nbn:hr:105:575985

S. Krüger, "Učestalost komponenata metaboličkog sindroma i masne jetre u bolesnika s teškom bakterijskom infekcijom", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:105:575985

Metadata
TitleUčestalost komponenata metaboličkog sindroma i masne jetre u bolesnika s teškom bakterijskom infekcijom
Title (english)Frequency of metabolic syndrome components and fatty liver in patients with severe bacterial infection
AuthorSanja Krüger
MentorNeven Papić (mentor)
Committee memberAdriana Vince (predsjednik povjerenstva)
Committee memberGoran Tešović (član povjerenstva)
Committee memberNeven Papić (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
(Department of Infectious Diseases)
Zagreb
Defense date and country2023-07-13, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Infectology
Abstract
Metabolički sindrom i masna jetra česti su metabolički poremećaji koji nose značajan kardiovaskularni rizik te rizik za kroničnu jetrenu bolest. Ta dva entiteta isprepletena su u mreži patofizioloških mehanizama koji dovode do modulacije imunološkog odgovora, što bi mogla biti podloga za povećani rizik od infekcija. Cilj ovog rada bio je istražiti prevalenciju komponenata metaboličkog sindroma i masne jetre u hospitaliziranih bolesnika sa teškim bakterijskim infekcijama. Radi se o presječnom istraživanju na 319 ispitanika hospitaliziranih na Klinici za infektivne bolesti “Dr. Fran Mihaljević” u razdoblju od siječnja do prosinca 2022. godine. Osim bilježenja učestalosti navedenih stanja, ispitanici su grupirani prema dobi, spolu, kliničkom sindromu, stupnju steatoze i fibroze. Izračunate su ukupne prevalencije te prevalencije po kliničkim sinromima za pojedine komponente metaboličkog sindroma i NAFLD. Ispitanici su podijeljeni prema NAFLD statusu u dvije skupine koje su zatim uspoređivane s obzirom na prisutnost komponenata metaboličkog sindroma. Rezultati su naposlijetku stavljeni u kontekst dostupne literature.
Abstract (english)
Metabolic syndrome and fatty liver are common metabolic disorders that carry significant cardiovascular risk and risk for chronic liver disease. These two entities are intertwined in a network of pathophysiological mechanisms that lead to modulation of the immune response, which could be the basis for an increased risk of infections. The aim of this study was to investigate this relationship and determine the prevalence of metabolic syndrome components and fatty liver in hospitalized patients with severe bacterial infections. This is a cross-sectional study conducted on 319 patients hospitalized at the Clinic for Infectious Diseases “Dr. Fran Mihaljević" from January to December 2022. In addition to recording the frequency of the mentioned conditions, the participants were grouped according to age, gender, clinical syndrome, degree of steatosis and fibrosis. Total prevalences and prevalences per clinical syndrome were calculated for individual components of metabolic syndrome and NAFLD. The participants were divided into two groups based on NAFLD status, which were then compared regarding the presence of metabolic syndrome components. The results were ultimately contextualised with the available literature.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:575985
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-10-25 12:20:15