Photoaging is a form of extrinsic skin aging and a result of chronic exposure to solar radiation. Exposure to external factors, of which ultraviolet radiation plays a key role, accelerates the physiological process of skin aging. In photochemical reactions harmful photoproducts and reactive oxygen species are formed whose effect on cellular and molecular mechanisms is manifested by structural and functional changes in the cell and extracellular matrix. The skin loses firmness and elasticity due to the breakdown of the structural components of the extracellular matrix, collagen and elastin, and the accumulation of non-functional proteins. Photoaged skin is thickened, wrinkled and dry, and various pigmentation changes and telangiectasias are noticeable. Chronic exposure to ultraviolet radiation increases the risk of developing precancerous lesions and malignant tumors due to the interaction of ultraviolet radiation with genetic material, causing mutations in the regions of genes for tumor suppressor proteins. Diagnostics of changes caused by photoaging relies on a physical examination, supplemented by dermoscopy for the purpose of analyzing and differentiating pigmentary changes. All formations of suspicious appearance need to be biopsied and pathohistologically analyzed. Adherence to sun protection measures is the best method of slowing down photoaging of the skin. Therapeutic options for reduction of the signs of aging are numerous today, and their selection depends on the degree of skin damage. We distinguish between non-invasive, local therapy with retinoids and dermocosmetics, a more aggressive method of chemical peeling and application of dermal fillers, and invasive surgical methods such as dermabrasion, laser application and face-lift surgery.