Multiple sclerosis (MS) is an autoimmune disease with chronic progressive course. The immune system in the disease damages the myelin lining of the nerves, leading to a weakened axon conduction, which is manifested by neurological outbursts depending on the location of the lesion. The most common symptoms are transverse myelitis, optic neuritis and somatosensory disturbances. Since urination is regulated from multiple centers located in different locations in the nervous system, lesions at any of these locations can lead to urinary disturbances, focusing on lesions in the spinal cord and brain stem. In diagnosing disease, the golden paraclinical standard is Magnetic resonance imaging (MRI), and evoked potentials (EP) can be used to identify clinically asymptomatic lesions. Patients undergo a neurological examination with an emphasis on large functional systems called Expanded Disability Status Scale (EDSS). Since 80% of MS patients present with urinary dysfunction during the course of the disease, there are also specialized questionnaires on bladder reactivity and quality of life by which the problem of urination is quickly objectified. In addition to disease-modifying therapy, specific treatment of the urinary tract is important either pharmacologically (anticholinergics, antimuscarinics, beta adrenergics, alpha blockers) or physical therapy modalities such as Kegel's exercises supported by biofeedback and electrical and magnetic stimulation. Neurostimulation is also highlighted as a method that could take an important place in the treatment of urinary dysfunction in the future and thus significantly improve patients' quality of life.