prikaz prve stranice dokumenta Circulating Cell-Free Tumor Deoxyribonucleic Acid Analysis as a Tool for the Diagnosis and Monitoring of Pediatric Solid Tumors
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Scientific paper - Original scientific paper
Circulating Cell-Free Tumor Deoxyribonucleic Acid Analysis as a Tool for the Diagnosis and Monitoring of Pediatric Solid Tumors
Turkish Archives of Pediatrics, 58 (2023), 3; 241-249. https://doi.org/10.5152/TurkArchPediatr.2023.23014
Zaninović, Luca; Bašković, Marko; Katušić Bojanac, Ana; Ježek, Davor

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Zaninović, L., Bašković, M., Katušić Bojanac, A. & Ježek, D. (2023). Circulating Cell-Free Tumor Deoxyribonucleic Acid Analysis as a Tool for the Diagnosis and Monitoring of Pediatric Solid Tumors. Turkish Archives of Pediatrics, 58. (3), 241-249. doi: 10.5152/TurkArchPediatr.2023.23014

Zaninović, Luca, et al. "Circulating Cell-Free Tumor Deoxyribonucleic Acid Analysis as a Tool for the Diagnosis and Monitoring of Pediatric Solid Tumors." Turkish Archives of Pediatrics, vol. 58, no. 3, 2023, pp. 241-249. https://doi.org/10.5152/TurkArchPediatr.2023.23014

Zaninović, Luca, Marko Bašković, Ana Katušić Bojanac and Davor Ježek. "Circulating Cell-Free Tumor Deoxyribonucleic Acid Analysis as a Tool for the Diagnosis and Monitoring of Pediatric Solid Tumors." Turkish Archives of Pediatrics 58, no. 3 (2023): 241-249. https://doi.org/10.5152/TurkArchPediatr.2023.23014

Zaninović, L., et al. (2023) 'Circulating Cell-Free Tumor Deoxyribonucleic Acid Analysis as a Tool for the Diagnosis and Monitoring of Pediatric Solid Tumors', Turkish Archives of Pediatrics, 58(3), pp. 241-249. doi: 10.5152/TurkArchPediatr.2023.23014

Zaninović L, Bašković M, Katušić Bojanac A, Ježek D. Circulating Cell-Free Tumor Deoxyribonucleic Acid Analysis as a Tool for the Diagnosis and Monitoring of Pediatric Solid Tumors. Turkish Archives of Pediatrics [Internet]. 2023 May [cited 2024 November 22];58(3):241-249. doi: 10.5152/TurkArchPediatr.2023.23014

L. Zaninović, M. Bašković, A. Katušić Bojanac and D. Ježek, "Circulating Cell-Free Tumor Deoxyribonucleic Acid Analysis as a Tool for the Diagnosis and Monitoring of Pediatric Solid Tumors", Turkish Archives of Pediatrics, vol. 58, no. 3, pp. 241-249, May 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:670060. [Accessed: 22 November 2024]

Metadata
Title (english)Circulating Cell-Free Tumor Deoxyribonucleic Acid Analysis as a Tool for the Diagnosis and Monitoring of Pediatric Solid Tumors
AuthorLuca Zaninović
AuthorMarko Bašković
AuthorAna Katušić Bojanac
AuthorDavor Ježek
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Histology and Embryology)
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Medical Biology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Cytology, Histology and Embryology
Abstract (english)
The utility of cell-free tumor deoxyribonucleic acid analysis is currently being evaluated in a wide range of clinical studies. The validity of cell-free tumor deoxyribonucleic acid analysis methods used for screening and detecting malignant diseases, monitoring the effectiveness of treatment and disease progression, and identifying potential relapse is tested. Molecular technologies used for cell-free tumor deoxyribonucleic acid analysis include targeted polymerase chain reaction assays and next-generation sequencing approaches along with newly introduced epigenetic analysis methods such as methylation-specific polymerase chain reaction. The aim of this review was to compare the methods, pitfalls, and advantages of tests developed for the analysis of cell-free tumor deoxyribonucleic acid in the diagnosis and treatment of pediatric solid tumors. For this purpose, the PubMed database was searched for articles published in the last 10 years, in English, that investigated a human cohort aged 0 to 18 years. A total of 272 references were analyzed. A total of 33 studies were included in the review. Cell-free tumor deoxyribonucleic acid analysis has emerged as a promising novel approach that could potentially bring a significant improvement in the field of pediatric oncology, but the implementation of cell-free tumor deoxyribonucleic acid in clinical practice is largely hindered by the lack of standardized methods for processing and analysis.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleTurkish Archives of Pediatrics
Numberingvol. 58, no. 3, pp. 241-249
e-ISSN2757-6256
DOIhttps://doi.org/10.5152/TurkArchPediatr.2023.23014
URN:NBNurn:nbn:hr:105:670060
Publication2023-05
Document URLhttps://turkarchpediatr.org/en/circulating-cell-free-tumor-deoxyribonucleic-acid-analysis-as-a-tool-for-the-diagnosis-and-monitoring-of-pediatric-solid-tumors-131529\
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-11-09 12:18:31