prikaz prve stranice dokumenta Evaluation of vision-related quality of life in patients after vitrectomy following idiopathic epiretinal membrane
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doctoral thesis
Evaluation of vision-related quality of life in patients after vitrectomy following idiopathic epiretinal membrane
Zagreb: University of Zagreb, School of Medicine, 2023. urn:nbn:hr:105:705291
Bajraktari, Gentian
University of Zagreb
School of Medicine

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Bajraktari, G. (2023). Evaluation of vision-related quality of life in patients after vitrectomy following idiopathic epiretinal membrane (Doctoral thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:705291

Bajraktari, Gentian. "Evaluation of vision-related quality of life in patients after vitrectomy following idiopathic epiretinal membrane." Doctoral thesis, University of Zagreb, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:105:705291

Bajraktari, Gentian. "Evaluation of vision-related quality of life in patients after vitrectomy following idiopathic epiretinal membrane." Doctoral thesis, University of Zagreb, School of Medicine, 2023. https://urn.nsk.hr/urn:nbn:hr:105:705291

Bajraktari, G. (2023). 'Evaluation of vision-related quality of life in patients after vitrectomy following idiopathic epiretinal membrane', Doctoral thesis, University of Zagreb, School of Medicine, accessed 30 December 2024, https://urn.nsk.hr/urn:nbn:hr:105:705291

Bajraktari G. Evaluation of vision-related quality of life in patients after vitrectomy following idiopathic epiretinal membrane [Doctoral thesis]. Zagreb: University of Zagreb, School of Medicine; 2023 [cited 2024 December 30] Available at: https://urn.nsk.hr/urn:nbn:hr:105:705291

G. Bajraktari, "Evaluation of vision-related quality of life in patients after vitrectomy following idiopathic epiretinal membrane", Doctoral thesis, University of Zagreb, School of Medicine, Zagreb, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:105:705291

Metadata
TitleEvaluation of vision-related quality of life in patients after vitrectomy following idiopathic epiretinal membrane
Title (croatian)Procjena kvalitete života s obzirom na vidnu funkciju u pacijenata nakon vitrektomije izvedene zbog idiopatske epiretinalne membrane
AuthorGentian Bajraktari
MentorTomislav Jukić (mentor)
Committee memberNenad Vukojević (predsjednik povjerenstva)
Committee memberIvanka Petric Vicković (član povjerenstva)
Committee memberSonja Jandroković (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
Zagreb
Defense date and country2023-11-08, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Ophthalmology
Universal decimal classification
(UDC)		617 - Surgery. Orthopaedics. Ophthalmology
Abstract
Background: To evaluate the impact of different intraocular tamponades on the vision-related quality of life (VRQOL) after idiopathic epiretinal membrane (IEM) surgery with epiretinal membrane peeling. Methods: We prospectively enrolled 90 patients diagnosed with IEM who underwent pars plana vitrectomy (PPV). Patients were consecutively assigned to either the air tamponade (air) group (45 patients) or the balanced salt solutions (BSS) tamponade group (45 patients). The following data were collected before and after surgery and compared between two groups: VRQOL, best corrected visual acuity (BCVA), intraocular pressure (IOP), metamorphopsia, contrast sensitivity (CS), and central macular thickness (CMT). The BCVA, IOP, CMT, CS, metamorphopsia score, each VFQ-25 subscale, and the composite scores have been compared between each pair of three-time points by using a paired sample t-test. Mean difference values have been compared between the two groups, the air group and the BSS group, by using an independent t-test. P-value < 0.05 was considered statistically significant. Results: PPV was performed in 90 eyes. At baseline, there were no significant differences between the two groups. At 6 months postoperatively, VRQOL (p < 0.001), BCVA (p < 0.001), CMT (p < 0.001), CS (p < 0.001), and metamorphopsia (p < 0.001) improved significantly in comparison to baseline, without significant differences between the air tamponade and BSS groups. Conclusion: Removing IEM significantly improved visual function and VRQOL. Despite improvements, our study showed no difference postoperatively whether air or BSS tamponade was used during surgery. As a result, air tamponade may not be a mandatory treatment for IEM surgery and provides no additional advantage compared with BSS tamponade.
Abstract (croatian)
UVOD: Idiopatska epiretinalna membrana (IEM) je fibrocelularna, nevaskularna proliferacija koja se razvija na površini unutarnje granične membrane mrežnice. Cilj operacije je optimizacija vidne oštrine, smanjenje metamorfopsije I uspostavljanje binokularnosti ako je ista bila narušena prije operacije. Svrha ovog istraživanja je procjena utjecaja različitih intraokularnih tamponada na kvalitetu života povezanu s vidom nakon operacije IEM i ljuštenja epiretinalne membrane. METODE: U ovo randomizirano, kontrolirano i prospektivno istraživanje uključeno je 90 pacijenata kojima je učinjena pars plana vitrektomija (PPV) zbog dijagnosticirane IEM na Klinici za očne bolesti, Kliničkog bolničkog centra Zagreb u razdoblju od rujna 2021. do ožujka 2023. Nakon zadovoljenja uključujućih kriterija, pacijenti su razvrstani u skupinu gdje je za tamponadu korišten zrak (zrak) ili u skupinu gdje je korištena balansirana otopina (eng. balanced salt solution – BSS). U svaku skupinu je nasumično razvrstano 45 pacijenata. Podatci koji su prikupljeni preoperativno, jedan mjesec i šest mjeseci nakon operacije jesu: upitnik kvalitete života povezane s vidnom funkcijom (eng. visual-related quality of life – VRQOL), najbolje korigirana vidna oštrina (best corrected visual acuity – BCVA), intraokularni tlak (IOT), metamorfopsija, kontrastna osjetljivost (eng. contrast sensitivity – CS) i centralna makularna debljina (central macular thickness – CMT). Sve statističke analize učinjene su koristeći IBM SPSS Statistic, verziju 23.0. Najbolje korigirana vidna oštrina, intraokularni tlak, razina metamorfopsije, kontrastna osjetljivost, centralna makularna debljina i svaka podljestvica VRQOL upitnika uspoređeni su između skupina zrak i BSS u sve tri vremenske točke koristeći parni t-test. Srednje vrijednosti uspoređene su između dvije skupine, zrak i BSS, koristeći t-test za nezavisne uzorke. P-vrijednost <0,05 smatrala se statistički značajnom. REZULTATI: Od 92 pacijenta, samo ih je 90 uključeno u istraživanje (45 u skupini zrak i 45 u skupini BSS), 1 je pacijent imao vitrealno krvarenje nakon prvog tjedna, a jedan pacijent se dobrovoljno povukao iz istraživanja. Usporedba predoperativnih podataka pokazala je da nema statistički značajne razlike između dvije skupina. Šest mjeseci nakon operacije vidljivo je statistički značajno poboljšanje VRQOL (p<0.001), BCVA (p<0.001), CMT (p<0.001), CS (p<0.001) i metamorfopsije (p<0.001) u usporedbi s preoperativnim podatcima, bez statistički značajne razlike između skupina zrak I BSS. ZAKLJUČAK: Uklanjanje IEM značajno poboljšava vidnu funkciju i kvalitetu života povezanu s vidom. Unatoč poboljšanju, naše istraživanje nije pokazalo postoperativnu razliku u korištenju tamponade zrakom ili BSS-om. Sukladno tome, tamponada zrakom ne pokazuje dodatnu prednost nad tamponadom BSS- om te se ne nameće kao obavezan izbor tamponade u operaciji idiopatske epiretinalne membrane.
Keywords
Keywords (croatian)
Languageenglish
URN:NBNurn:nbn:hr:105:705291
Study programmeTitle: Biomedicine and Health Sciences
Study programme type: university
Study level: postgraduate
Academic / professional title: doktor/doktorica znanosti, područje biomedicine i zdravstvo (doktor/doktorica znanosti, područje biomedicine i zdravstvo)
Type of resourceText
Extent70 str.
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-11-14 09:11:48