prikaz prve stranice dokumenta The association of brain-derived neurotrophic factor with the diagnosis and treatment response in depression
Embargo period 2024-05-01
Scientific paper - Original scientific paper
The association of brain-derived neurotrophic factor with the diagnosis and treatment response in depression
Expert Review of Molecular Diagnostics, 23 (2023), 4; 283-296. https://doi.org/10.1080/14737159.2023.2200937
Nikolac Perković, Matea; Gredičak, Martin; Šagud, Marina; Nedić Erjavec, Gordana; Uzun, Suzana; Pivac, Nela

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Nikolac Perković, M., Gredičak, M., Šagud, M., Nedić Erjavec, G., Uzun, S. & Pivac, N. (2023). The association of brain-derived neurotrophic factor with the diagnosis and treatment response in depression. Expert Review of Molecular Diagnostics, 23. (4), 283-296. doi: 10.1080/14737159.2023.2200937

Nikolac Perković, Matea, et al. "The association of brain-derived neurotrophic factor with the diagnosis and treatment response in depression." Expert Review of Molecular Diagnostics, vol. 23, no. 4, 2023, pp. 283-296. https://doi.org/10.1080/14737159.2023.2200937

Nikolac Perković, Matea, Martin Gredičak, Marina Šagud, Gordana Nedić Erjavec, Suzana Uzun and Nela Pivac. "The association of brain-derived neurotrophic factor with the diagnosis and treatment response in depression." Expert Review of Molecular Diagnostics 23, no. 4 (2023): 283-296. https://doi.org/10.1080/14737159.2023.2200937

Nikolac Perković, M., et al. (2023) 'The association of brain-derived neurotrophic factor with the diagnosis and treatment response in depression', Expert Review of Molecular Diagnostics, 23(4), pp. 283-296. doi: 10.1080/14737159.2023.2200937

Nikolac Perković M, Gredičak M, Šagud M, Nedić Erjavec G, Uzun S, Pivac N. The association of brain-derived neurotrophic factor with the diagnosis and treatment response in depression. Expert Review of Molecular Diagnostics [Internet]. 2023 April 14 [cited 2024 April 29];23(4):283-296. doi: 10.1080/14737159.2023.2200937

M. Nikolac Perković, M. Gredičak, M. Šagud, G. Nedić Erjavec, S. Uzun and N. Pivac, "The association of brain-derived neurotrophic factor with the diagnosis and treatment response in depression", Expert Review of Molecular Diagnostics, vol. 23, no. 4, pp. 283-296, April 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:267765. [Accessed: 29 April 2024]

Metadata
Title (english)The association of brain-derived neurotrophic factor with the diagnosis and treatment response in depression
AuthorMatea Nikolac Perković
AuthorMartin Gredičak
AuthorMarina Šagud
AuthorGordana Nedić Erjavec
AuthorSuzana Uzun
AuthorNela Pivac
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Psychiatry and Psychological Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Psychiatry
Abstract (english)
Introduction: Recent evidence from the studies evaluating the association between brain-derived neurotrophic factor (BDNF) concentration/levels, BDNF Val66Met (rs6265) polymorphism, and major depressive disorders, referred as depression, and the association between BDNF levels and/or BDNF Val66Met with the treatment response in depression is presented. Areas covered: This mini review focuses on the changes in the peripheral BDNF levels in blood (serum, plasma, platelets) in patients with depression before or after treatment with antidepressant drugs or different therapeutic strategies. In addition, this review describes the recent data on the possible association between different antidepressants/therapeutic strategies and the particular BDNF Val66Met genotypes, evaluating the risk alleles associated with the response in patients with depression. Expert opinion: BDNF has an important role in the pathophysiology and treatment response in depression. Most data reveal that peripheral BDNF levels are lower before than after antidepressant treatment and might be used as potential biomarkers of therapeutic response. Novel therapeutic strategies should target restoring/increasing BDNF levels.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleExpert Review of Molecular Diagnostics
Numberingvol. 23, no. 4, pp. 283-296
p-ISSN1473-7159
e-ISSN1744-8352
DOIhttps://doi.org/10.1080/14737159.2023.2200937
URN:NBNurn:nbn:hr:105:267765
Publication2023-04-14
Document URLhttps://www.tandfonline.com/doi/full/10.1080/14737159.2023.2200937
Type of resourceText
Access conditionsEmbargoed access
Embargo expiration date: 2024-05-01
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2024-01-08 08:42:18