prikaz prve stranice dokumenta Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry
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Scientific paper - Original scientific paper
Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry
Journal of Clinical Medicine, 12 (2023), 3; 896. https://doi.org/10.3390/jcm12030896
De Luca, Giuseppe; Manzo-Silberman, Stephane; Algowhary, Magdy; Uguz, Berat; Oliveira, Dinaldo C.; Ganyukov, Vladimir; Busljetik, Oliver; Cercek, Miha; Okkels, Lisette; Loh, Poay Huan; Calmac, Lucian; Ferrer, Gerard Roura i; Quadros, Alexandre; Milewski, Marek; Scotto di Uccio, Fortunato; von Birgelen, Clemens; Versaci, Francesco; Ten Berg, Jurrien; Casella, Gianni; Wong Sung Lung, Aaron; Kala, Petr; Díez Gil, José Luis; Carrillo, Xavier; Dirksen, Maurits; Becerra, Victor; Lee, Michael Kang-yin; Juzar, Dafsah Arifa; de Moura Joaquim, Rodrigo; Paladino, Roberto; Miličić, Davor; Davlouros, Periklis; Bakraceski, Nikola; Zilio, Filippo; Donazzan, Luca; Kraaijeveld, Adriaan; Galasso, Gennaro; Arpad, Lux; Marinucci, Lucia; Guiducci, Vincenzo; Menichelli, Maurizio; Scoccia, Alessandra; Yamac, Aylin Hatice; Ugur Mert, Kadir; Flores Rios, Xacobe; Kovarnik, Tomas; Kidawa, Michal; Moreu, Josè; Flavien, Vincent; Fabris, Enrico; Martínez-Luengas, Iñigo Lozano; Boccalatte, Marco; Ojeda, Francisco Bosa; Arellano-Serrano, Carlos; Caiazzo, Gianluca; Cirrincione, Giuseppe; Kao, Hsien-Li; Forés, Juan Sanchis; Vignali, Luigi; Pereira, Helder; Ordoñez, Santiago; Arat Özkan, Alev; Scheller, Bruno; Lehtola, Heidi; Teles, Rui; Mantis, Christos; Antti, Ylitalo; Brum Silveira, João António; Zoni, Cesar Rodrigo; Bessonov, Ivan; Uccello, Giuseppe; Kochiadakis, George; Alexopulos, Dimitrios; Uribe, Carlos E.; Kanakakis, John; Faurie, Benjamin; Gabrielli, Gabriele; Barrios, Alejandro Gutierrez; Bachini, Juan Pablo; Rocha, Alex; Tam, Frankie C. C.; Rodriguez, Alfredo; Lukito, Antonia Anna; Saint-Joy, Veauthyelau; Pessah, Gustavo; Tuccillo, Andrea; Ielasi, Alfonso; Cortese, Giuliana; Parodi, Guido; Bouraghda, Mohamed Abed; Moura, Marcia; Kedhi, Elvin; Lamelas, Pablo; Suryapranata, Harry; Nardin, Matteo; Verdoia, Monica More authors...

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De Luca, G., Manzo Silberman, S., Algowhary, M., Uguz, B., Oliveira, D. C., Ganyukov, V. ... Verdoia, M. (2023). Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry. Journal of Clinical Medicine, 12. (3). doi: 10.3390/jcm12030896

De Luca, Giuseppe, et al. "Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry." Journal of Clinical Medicine, vol. 12, no. 3, 2023. https://doi.org/10.3390/jcm12030896

De Luca, Giuseppe, Stephane Manzo Silberman, Magdy Algowhary, Berat Uguz, Dinaldo C. Oliveira, Vladimir Ganyukov, Oliver Busljetik, et al. "Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry." Journal of Clinical Medicine 12, no. 3 (2023). https://doi.org/10.3390/jcm12030896

De Luca, G., et al. (2023) 'Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry', Journal of Clinical Medicine, 12(3). doi: 10.3390/jcm12030896

De Luca G, Manzo Silberman S, Algowhary M, Uguz B, Oliveira DC, Ganyukov V, and sur.. Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry. Journal of Clinical Medicine [Internet]. 2023 January 23 [cited 2024 May 07];12(3). doi: 10.3390/jcm12030896

G. De Luca, et al., "Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry", Journal of Clinical Medicine, vol. 12, no. 3, January 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:321340. [Accessed: 07 May 2024]

Metadata
Title (english)Gender Difference in the Effects of COVID-19 Pandemic on Mechanical Reperfusion and 30-Day Mortality for STEMI: Results of the ISACS-STEMI COVID-19 Registry
AuthorGiuseppe De Luca
AuthorStephane Manzo-Silberman
AuthorMagdy Algowhary
AuthorBerat Uguz
AuthorDinaldo C. Oliveira
AuthorVladimir Ganyukov
AuthorOliver Busljetik
AuthorMiha Cercek
AuthorLisette Okkels
AuthorPoay Huan Loh
AuthorLucian Calmac
AuthorGerard Roura i Ferrer
AuthorAlexandre Quadros
AuthorMarek Milewski
AuthorFortunato Scotto di Uccio
AuthorClemens von Birgelen
AuthorFrancesco Versaci
AuthorJurrien Ten Berg
AuthorGianni Casella
AuthorAaron Wong Sung Lung
AuthorPetr Kala
AuthorJosé Luis Díez Gil
AuthorXavier Carrillo
AuthorMaurits Dirksen
AuthorVictor Becerra
AuthorMichael Kang-yin Lee
AuthorDafsah Arifa Juzar
AuthorRodrigo de Moura Joaquim
AuthorRoberto Paladino
AuthorDavor Miličić
AuthorPeriklis Davlouros
AuthorNikola Bakraceski
AuthorFilippo Zilio
AuthorLuca Donazzan
AuthorAdriaan Kraaijeveld
AuthorGennaro Galasso
AuthorLux Arpad
AuthorLucia Marinucci
AuthorVincenzo Guiducci
AuthorMaurizio Menichelli
AuthorAlessandra Scoccia
AuthorAylin Hatice Yamac
AuthorKadir Ugur Mert
AuthorXacobe Flores Rios
AuthorTomas Kovarnik
AuthorMichal Kidawa
AuthorJosè Moreu
AuthorVincent Flavien
AuthorEnrico Fabris
AuthorIñigo Lozano Martínez-Luengas
AuthorMarco Boccalatte
AuthorFrancisco Bosa Ojeda
AuthorCarlos Arellano-Serrano
AuthorGianluca Caiazzo
AuthorGiuseppe Cirrincione
AuthorHsien-Li Kao
AuthorJuan Sanchis Forés
AuthorLuigi Vignali
AuthorHelder Pereira
AuthorSantiago Ordoñez
AuthorAlev Arat Özkan
AuthorBruno Scheller
AuthorHeidi Lehtola
AuthorRui Teles
AuthorChristos Mantis
AuthorYlitalo Antti
AuthorJoão António Brum Silveira
AuthorCesar Rodrigo Zoni
AuthorIvan Bessonov
AuthorGiuseppe Uccello
AuthorGeorge Kochiadakis
AuthorDimitrios Alexopulos
AuthorCarlos E. Uribe
AuthorJohn Kanakakis
AuthorBenjamin Faurie
AuthorGabriele Gabrielli
AuthorAlejandro Gutierrez Barrios
AuthorJuan Pablo Bachini
AuthorAlex Rocha
AuthorFrankie C. C. Tam
AuthorAlfredo Rodriguez
AuthorAntonia Anna Lukito
AuthorVeauthyelau Saint-Joy
AuthorGustavo Pessah
AuthorAndrea Tuccillo
AuthorAlfonso Ielasi
AuthorGiuliana Cortese
AuthorGuido Parodi
AuthorMohamed Abed Bouraghda
AuthorMarcia Moura
AuthorElvin Kedhi
AuthorPablo Lamelas
AuthorHarry Suryapranata
AuthorMatteo Nardin
AuthorMonica Verdoia
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Background: Several reports have demonstrated the impact of the COVID-19 pandemic on the management and outcome of patients with ST-segment elevation myocardial infarction (STEMI). The aim of the current analysis is to investigate the potential gender difference in the effects of the COVID-19 pandemic on mechanical reperfusion and 30-day mortality for STEMI patients within the ISACS-STEMI COVID-19 Registry. Methods: This retrospective multicenter registry was performed in high-volume primary percutaneous coronary intervention (PPCI) centers on four continents and included STEMI patients undergoing PPCIs in March-June 2019 and 2020. Patients were divided according to gender. The main outcomes were the incidence and timing of the PPCI, (ischemia time ≥ 12 h and door-to-balloon ≥ 30 min) and in-hospital or 30-day mortality. Results: We included 16683 STEMI patients undergoing PPCIs in 109 centers. In 2020 during the pandemic, there was a significant reduction in PPCIs compared to 2019 (IRR 0.843 (95% CI: 0.825-0.861, p < 0.0001). We did not find a significant gender difference in the effects of the COVID-19 pandemic on the numbers of STEMI patients, which were similarly reduced from 2019 to 2020 in both groups, or in the mortality rates. Compared to prepandemia, 30-day mortality was significantly higher during the pandemic period among female (12.1% vs. 8.7%; adjusted HR [95% CI] = 1.66 [1.31-2.11], p < 0.001) but not male patients (5.8% vs. 6.7%; adjusted HR [95% CI] = 1.14 [0.96-1.34], p = 0.12). Conclusions: The COVID-19 pandemic had a significant impact on the treatment of patients with STEMI, with a 16% reduction in PPCI procedures similarly observed in both genders. Furthermore, we observed significantly increased in-hospital and 30-day mortality rates during the pandemic only among females. Trial registration number: NCT 04412655.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleJournal of Clinical Medicine
Numberingvol. 12, no. 3, 896
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm12030896
URN:NBNurn:nbn:hr:105:321340
Publication2023-01-23
Document URLhttps://www.mdpi.com/2077-0383/12/3/896
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) icon
Created on2024-01-16 08:57:54