prikaz prve stranice dokumenta Oxidative homeostasis in follicular fluid and reproductive outcomes – from bench to bedside
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Scientific paper - Review paper
Oxidative homeostasis in follicular fluid and reproductive outcomes – from bench to bedside
Menopausal Review, 21 (2022), 4; 276-284. https://doi.org/10.5114/pm.2022.124019
Zec, Ivana; Šprem Goldštajn, Marina; Kuna, Krunoslav; Mikuš, Mislav; Stabile, Guglielmo; Bianco, Bianca; Buzzaccarini, Giovanni; Laganà, Antonio Simone

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

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Zec, I., Šprem Goldštajn, M., Kuna, K., Mikuš, M., Stabile, G., Bianco, B. ... Laganà, A. S. (2022). Oxidative homeostasis in follicular fluid and reproductive outcomes – from bench to bedside. Menopausal Review, 21. (4), 276-284. doi: 10.5114/pm.2022.124019

Zec, Ivana, et al. "Oxidative homeostasis in follicular fluid and reproductive outcomes – from bench to bedside." Menopausal Review, vol. 21, no. 4, 2022, pp. 276-284. https://doi.org/10.5114/pm.2022.124019

Zec, Ivana, Marina Šprem Goldštajn, Krunoslav Kuna, Mislav Mikuš, Guglielmo Stabile, Bianca Bianco, Giovanni Buzzaccarini and Antonio Simone Laganà. "Oxidative homeostasis in follicular fluid and reproductive outcomes – from bench to bedside." Menopausal Review 21, no. 4 (2022): 276-284. https://doi.org/10.5114/pm.2022.124019

Zec, I., et al. (2022) 'Oxidative homeostasis in follicular fluid and reproductive outcomes – from bench to bedside', Menopausal Review, 21(4), pp. 276-284. doi: 10.5114/pm.2022.124019

Zec I, Šprem Goldštajn M, Kuna K, Mikuš M, Stabile G, Bianco B, and sur.. Oxidative homeostasis in follicular fluid and reproductive outcomes – from bench to bedside. Menopausal Review [Internet]. 2022 December [cited 2024 May 05];21(4):276-284. doi: 10.5114/pm.2022.124019

I. Zec, et al., "Oxidative homeostasis in follicular fluid and reproductive outcomes – from bench to bedside", Menopausal Review, vol. 21, no. 4, pp. 276-284, December 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:599125. [Accessed: 05 May 2024]

Metadata
Title (english)Oxidative homeostasis in follicular fluid and reproductive outcomes – from bench to bedside
AuthorIvana Zec
AuthorMarina Šprem Goldštajn
AuthorKrunoslav Kuna
AuthorMislav Mikuš
AuthorGuglielmo Stabile
AuthorBianca Bianco
AuthorGiovanni Buzzaccarini
AuthorAntonio Simone Laganà
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Gynecology and Obstetrics)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Geriatrics
Abstract (english)
Free radicals and oxidant molecules are part of our organism in a stable balance. However, when addressing female infertility, questions about their role in oocyte quality arise. This review outlines the major alterations of redox homeostasis in the follicular fluid through pathophysiological conditions in female reproduction and its potential effect on IVF outcome. A review of the literature was accurately performed. Manuscripts investigating follicular fluid biomarkers, especially related to oxidant molecules, were screened and used in this review. Studies assessing the follicular reactive species were found and screened. Moreover, studies assessing the IVF outcomes related to biomarkers were considered. The results are provided in an analytical pathway. The study of biomarkers confirms the shift to enhanced oxidizing modification of macromolecules and antioxidative consumption in the follicular fluid of women undergoing IVF treatment. A lack of congruency in methods appears to be marked in the design of scientific studies. However, it is not clear whether redox disbalance has a disruptive effect on the oocyte competence or whether it plays a role in the oocyte maturation process. Red-ox balance plays a questionable role in IVF outcomes. Possible further insights may consider the antioxidant role of adjuvants during controlled ovarian stimulation cycles.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMenopausal Review
Numberingvol. 21, no. 4, pp. 276-284
p-ISSN1643-8876
DOIhttps://doi.org/10.5114/pm.2022.124019
URN:NBNurn:nbn:hr:105:599125
Publication2022-12
Document URLhttps://www.termedia.pl/doi/10.5114/pm.2022.124019
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) icon
Created on2024-01-23 08:54:31