prikaz prve stranice dokumenta Presentation of Graves’ orbitopathy within European Group On Graves’ Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III)
  Download
PDF 441.37 KB
Scientific paper - Original scientific paper
Presentation of Graves’ orbitopathy within European Group On Graves’ Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III)
British Journal of Ophthalmology, 108 (2024), 2; 294-300. https://doi.org/10.1136/bjo-2022-322442
Schuh, Anna; Ayvaz, Goksun; Baldeschi, Lelio; Baretić, Maja; Bechtold, Dorte; Boschi, Antonella; Brix, Thomas Heiberg; Burlacu, Maria-Cristina; Ciric, Jasmina; Covelli, Danila; Currò, Nicola; Donati, Simone; Eckstein, Anja K; Fichter, Nicole; Führer, Dagmar; Horn, Maren; Jabłońska-Pawlak, Anna; Juri Mandić, Jelena; Kahaly, George J; Konuk, Onur; Langbein, Amelie; Lanzolla, Giulia; Marcocci, Claudio; Marinò, Michele; Miśkiewicz, Piotr; Beleslin, Biljana Nedeljkovic; Pérez-Lázaro, Antonia; Pérez-López, Marta; Ponto, Katharina A; Quinn, Anthony; Rudofsky, Gottfried; Salvi, Mario; Schittkowski, Michael P; Tanda, Maria Laura; Toruner, Fusun; Vaidya, Bijay; Hintschich, Christoph R More authors...

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Schuh, A., Ayvaz, G., Baldeschi, L., Baretić, M., Bechtold, D., Boschi, A. ... Hintschich, C. R. (2024). Presentation of Graves’ orbitopathy within European Group On Graves’ Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III). British Journal of Ophthalmology, 108. (2), 294-300. doi: 10.1136/bjo-2022-322442

Schuh, Anna, et al. "Presentation of Graves’ orbitopathy within European Group On Graves’ Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III)." British Journal of Ophthalmology, vol. 108, no. 2, 2024, pp. 294-300. https://doi.org/10.1136/bjo-2022-322442

Schuh, Anna, Goksun Ayvaz, Lelio Baldeschi, Maja Baretić, Dorte Bechtold, Antonella Boschi, Thomas Heiberg Brix, et al. "Presentation of Graves’ orbitopathy within European Group On Graves’ Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III)." British Journal of Ophthalmology 108, no. 2 (2024): 294-300. https://doi.org/10.1136/bjo-2022-322442

Schuh, A., et al. (2024) 'Presentation of Graves’ orbitopathy within European Group On Graves’ Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III)', British Journal of Ophthalmology, 108(2), pp. 294-300. doi: 10.1136/bjo-2022-322442

Schuh A, Ayvaz G, Baldeschi L, Baretić M, Bechtold D, Boschi A, and sur.. Presentation of Graves’ orbitopathy within European Group On Graves’ Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III). British Journal of Ophthalmology [Internet]. 2024 February [cited 2024 December 01];108(2):294-300. doi: 10.1136/bjo-2022-322442

A. Schuh, et al., "Presentation of Graves’ orbitopathy within European Group On Graves’ Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III)", British Journal of Ophthalmology, vol. 108, no. 2, pp. 294-300, February 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:549849. [Accessed: 01 December 2024]

Metadata
Title (english)Presentation of Graves’ orbitopathy within European Group On Graves’ Orbitopathy (EUGOGO) centres from 2012 to 2019 (PREGO III)
AuthorAnna Schuh
AuthorGoksun Ayvaz
AuthorLelio Baldeschi
AuthorMaja Baretić
AuthorDorte Bechtold
AuthorAntonella Boschi
AuthorThomas Heiberg Brix
AuthorMaria-Cristina Burlacu
AuthorJasmina Ciric
AuthorDanila Covelli
AuthorNicola Currò
AuthorSimone Donati
AuthorAnja K Eckstein
AuthorNicole Fichter
AuthorDagmar Führer
AuthorMaren Horn
AuthorAnna Jabłońska-Pawlak
AuthorJelena Juri Mandić
AuthorGeorge J Kahaly
AuthorOnur Konuk
AuthorAmelie Langbein
AuthorGiulia Lanzolla
AuthorClaudio Marcocci
AuthorMichele Marinò
AuthorPiotr Miśkiewicz
AuthorBiljana Nedeljkovic Beleslin
AuthorAntonia Pérez-Lázaro
AuthorMarta Pérez-López
AuthorKatharina A Ponto
AuthorAnthony Quinn
AuthorGottfried Rudofsky
AuthorMario Salvi
AuthorMichael P Schittkowski
AuthorMaria Laura Tanda
AuthorFusun Toruner
AuthorBijay Vaidya
AuthorChristoph R Hintschich
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Ophthalmology and Optometry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Ophthalmology
Abstract (english)
Background: Graves' orbitopathy (GO) is subject to epidemiological and care-related changes. Aim of the survey was to identify trends in presentation of GO to the European Group On Graves' Orbitopathy (EUGOGO) tertiary referral centres and initial management over time. Methods: Prospective observational multicentre study. All new referrals with diagnosis of GO within September-December 2019 were included. Clinical and demographic characteristics, referral timelines and initial therapeutic decisions were recorded. Data were compared with a similar EUGOGO survey performed in 2012. Results: Besides age (mean age: 50.5±13 years vs 47.7±14 years; p 0.007), demographic characteristics of 432 patients studied in 2019 were similar to those in 2012. In 2019, there was a decrease of severe cases (9.8% vs 14.9; p<0.001), but no significant change in proportion of active cases (41.3% vs 36.6%; p 0.217). After first diagnosis of GO, median referral time to an EUGOGO tertiary centre was shorter (2 (0-350) vs 6 (0-552) months; p<0.001) in 2019. At the time of first visit, more patients were already on antithyroid medications (80.2% vs 45.0%; p<0.001) or selenium (22.3% vs 3.0%; p<0.001). In 2019, the initial management plans for GO were similar to 2012, except for lid surgery (2.4% vs 13.9%; p<0.001) and prescription of selenium (28.5% vs 21.0%; p 0.027). Conclusion: GO patients are referred to tertiary EUGOGO centres in a less severe stage of the disease than before. We speculate that this might be linked to a broader awareness of the disease and faster and adequate delivered treatment.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleBritish Journal of Ophthalmology
Numberingvol. 108, no. 2, pp. 294-300
p-ISSN0007-1161
e-ISSN1468-2079
DOIhttps://doi.org/10.1136/bjo-2022-322442
URN:NBNurn:nbn:hr:105:549849
Publication2024-02
Document URLhttps://bjo.bmj.com/lookup/doi/10.1136/bjo-2022-322442
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2024-02-20 09:08:26