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master's thesis
Kronična upalna bolest crijeva u djece
Zagreb: University of Zagreb, School of Medicine, 2022. urn:nbn:hr:105:820032
Majkić, Bosiljka
University of Zagreb
School of Medicine

Institutional repository: Dr Med - University of Zagreb School of Medicine Digital Repository

Cite this document

Majkić, B. (2022). Kronična upalna bolest crijeva u djece (Master's thesis). Zagreb: University of Zagreb, School of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:820032

Majkić, Bosiljka. "Kronična upalna bolest crijeva u djece." Master's thesis, University of Zagreb, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:105:820032

Majkić, Bosiljka. "Kronična upalna bolest crijeva u djece." Master's thesis, University of Zagreb, School of Medicine, 2022. https://urn.nsk.hr/urn:nbn:hr:105:820032

Majkić, B. (2022). 'Kronična upalna bolest crijeva u djece', Master's thesis, University of Zagreb, School of Medicine, accessed 06 May 2024, https://urn.nsk.hr/urn:nbn:hr:105:820032

Majkić B. Kronična upalna bolest crijeva u djece [Master's thesis]. Zagreb: University of Zagreb, School of Medicine; 2022 [cited 2024 May 06] Available at: https://urn.nsk.hr/urn:nbn:hr:105:820032

B. Majkić, "Kronična upalna bolest crijeva u djece", Master's thesis, University of Zagreb, School of Medicine, Zagreb, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:105:820032

Metadata
TitleKronična upalna bolest crijeva u djece
Title (english)Inflammatory bowel disease in children
AuthorBosiljka Majkić
MentorIrena Senečić-Čala (mentor)
Committee memberJurica Vuković (predsjednik povjerenstva)
Committee memberMarija Jelušić (član povjerenstva)
Committee memberIrena Senečić-Čala (član povjerenstva)
GranterUniversity of Zagreb
School of Medicine
Zagreb
Defense date and country2022-09-08, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract
Kronične upalne bolesti crijeva (IBD) - Crohnova bolest, ulcerozni kolitis i neklasificirana upalna bolest crijeva sve se češće dijagnosticiraju u dječjoj i adolescentskoj dobi. Ove bolesti se razlikuju po lokalizaciji upale. Kod ulceroznog kolitisa bolest je ograničena na debelo crijevo, dok kod Crohnove bolesti upalom može biti zahvaćen cijeli gastrointestinalni trakt. Crijevo je organ koji se nalazi pod neprestanom imunološkom stimulacijom mikroba i antigena iz hrane. Kao odgovor na to dolazi do tzv. "fiziološke“ upale sluznice. Kod razvoja upalnih bolesti patološka upala zamjenjuje fiziološku. I dalje je nejasno je li riječ o abnormalnom odgovoru na uobičajene enteričke antigene ili o normalnom odgovoru na još neidentificirane mikrobe. Simptomi koje ima pacijent su važan indikator upale i aktivnosti same bolesti, ali su istovremeno i subjektivni, mogu biti potencirani drugim neupalnim činiteljima kao što su intestinalne strikture, malapsorpcija žučnih soli, nepodnošenje laktoze i brojnim drugima. Rano postavljanje dijagnoze je važno zbog boljeg terapijskog učinka. Klasičnu terapiju upalnih bolesti crijeva čine aminosalicilati, kortikosteroidi te imunomodulatorni lijekovi, a u novije vrijeme i biološka terapija. Konvencionalna terapija i dalje je prva i osnovna linija kod terapije upalnih bolesti crijeva svih lokalizacija i aktivnosti. Glavni ciljevi terapije su ublažavanje simptoma, postizanje remisije i kvalitetan život bolesnika.
Abstract (english)
Chronic inflammatory bowel disease (IBD) - Crohn's disease, ulcerative colitis and unclassified inflammatory bowel disease are increasingly being diagnosed in children and adolescents. These diseases differ in the localization of inflammation. In ulcerative colitis it is limited to the large intestine, while in Crohn's disease inflammation can affect the entire gastrointestinal tract. The gut is an organ that is under constant immune stimulation of microbes and antigens from food. In response to this comes the so-called. "physiological" mucositis. In the development of inflammatory diseases, pathological inflammation replaces physiological inflammation. It is further unclear whether this is an abnormal response to a common enteric antigen or a normal response to as yet unidentified microbes. Symptoms of the patient as an important indicator of inflammation and activity of the same disease, but also subjective, can be exacerbated by other non-inflammatory factors such as intestinal strictures, malabsorption of bile salts, lactose intolerance, constipation and many others. Early diagnosis is important for better therapeutic effect. Classical therapy of inflammatory bowel disease consists of aminosalicylates, corticosteroids and immunomodulatory drugs and recently biologic therapy. Conventional therapy is still the first and basic line in the treatment of inflammatory bowel disease of all localizations and activities.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:105:820032
Study programmeTitle: Studies in Nursing
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-02-21 13:20:12